Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VRK3
  • Mouse genes Vrk3
  • Rat genes Vrk3
  • Zfish genes vrk3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vrk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VRK3	IPI	UniProtKB:P61244	Human	PMID:25609649
Molecular Function	GO:0019903	protein phosphatase binding	VRK3	IDA		Human	PMID:22572157
Molecular Function	GO:0019903	protein phosphatase binding	Vrk3	IPI	PR:Q9D7X3	Mouse	PMID:18035061
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	VRK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	VRK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	VRK3	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Vrk3	IDA		Mouse	PMID:14645249
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Vrk3	IDA		Mouse	PMID:18035061
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	Vrk3	IPI	PR:Q9D7X3	Mouse	PMID:18035061
Biological Process	GO:0007519	skeletal muscle tissue development	VRK3	IGI	FB:FBgn0027504	Human	PMID:35140224

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern