Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VASP
  • Mouse genes Vasp
  • Rat genes Vasp
  • Zfish genes vaspa,vaspb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vasp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	VASP	HDA		Human	PMID:25468996
Molecular Function	GO:0005522	profilin binding	VASP	IPI	UniProtKB:P07737	Human	PMID:17914456
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9C026	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q702N8	Human	PMID:16631741
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q05655	Human	PMID:16940418
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q92636	Human	PMID:17599063
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:P22736	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q15418	Human	PMID:21423205
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9RI12	Human	PMID:21911467
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:P07737	Human	PMID:23153535
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9JJV2	Human	PMID:23153535
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9UQB8-4	Human	PMID:24076653
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:O95684	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q13296	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9NYB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9P2A4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q15942	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9NYB9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q15942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q8IZP0-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9C026	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9P2A4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:Q9UIG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VASP	IPI	UniProtKB:P12003	Human	PMID:8836115
Molecular Function	GO:0005515	protein binding	Vasp	IPI	UniProtKB:F2Z408	Mouse	PMID:20417104
Molecular Function	GO:0005515	protein binding	Vasp	IPI	PR:P70460	Mouse	PMID:15465019
Cellular Component	GO:0005829	cytosol	VASP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	VASP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	VASP	HDA		Human	PMID:20458337
Cellular Component	GO:0030175	filopodium	Vasp	IDA		Mouse	PMID:15148305
Cellular Component	GO:0030175	filopodium	Vasp	IDA		Mouse	PMID:15294161
Cellular Component	GO:0005925	focal adhesion	VASP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	VASP	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Vasp	IDA		Mouse	PMID:15148305
Cellular Component	GO:0030027	lamellipodium	Vasp	IDA		Mouse	PMID:15148305
Cellular Component	GO:0005886	plasma membrane	VASP	IDA		Human	GO_REF:0000052
Biological Process	GO:0030036	actin cytoskeleton organization	Vasp	IGI	MGI:MGI:108360	Mouse	PMID:15371503
Biological Process	GO:0007411	axon guidance	Vasp	IGI	MGI:MGI:108360	Mouse	PMID:15371503
Biological Process	GO:0001843	neural tube closure	Vasp	IGI	MGI:MGI:108360	Mouse	PMID:15371503
Biological Process	GO:0030838	positive regulation of actin filament polymerization	VASP	IDA		Human	PMID:23153535

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern