Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VASH2
  • Mouse genes Vash2
  • Rat genes Vash2
  • Zfish genes vash2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vash2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	VASH2	IDA		Human	PMID:29146869
Molecular Function	GO:0003779	actin binding	Vash2	IDA		Mouse	MGI:MGI:6102981|PMID:29146868
Molecular Function	GO:0004181	metallocarboxypeptidase activity	VASH2	IDA		Human	PMID:29146869
Molecular Function	GO:0004181	metallocarboxypeptidase activity	VASH2	IMP		Human	PMID:31171830
Molecular Function	GO:0004181	metallocarboxypeptidase activity	VASH2	IMP		Human	PMID:31235911
Molecular Function	GO:0004181	metallocarboxypeptidase activity	Vash2	IDA		Mouse	MGI:MGI:6102981|PMID:29146868
Molecular Function	GO:0004181	metallocarboxypeptidase activity	Vash2	IMP		Mouse	MGI:MGI:6383353|PMID:31324789
Molecular Function	GO:0008017	microtubule binding	VASH2	IDA		Human	PMID:31324789
Molecular Function	GO:0005515	protein binding	VASH2	IPI	UniProtKB:Q8N300	Human	PMID:29146869
Molecular Function	GO:0005515	protein binding	VASH2	IPI	UniProtKB:Q8N300	Human	PMID:31235911
Molecular Function	GO:0005515	protein binding	Vash2	IPI	UniProtKB:Q99LQ4	Mouse	MGI:MGI:6102981|PMID:29146868
Molecular Function	GO:0005515	protein binding	Vash2	IPI	UniProtKB:Q8N300	Mouse	MGI:MGI:6383353|PMID:31324789
Cellular Component	GO:0005737	cytoplasm	VASH2	IDA		Human	PMID:19204325
Cellular Component	GO:0005829	cytosol	VASH2	IDA		Human	GO_REF:0000052
Biological Process	GO:0061564	axon development	VASH2	IMP		Human	PMID:31324789
Biological Process	GO:0140253	cell-cell fusion	VASH2	IDA		Human	PMID:25184477
Biological Process	GO:0140253	cell-cell fusion	VASH2	IMP		Human	PMID:25184477
Biological Process	GO:0060716	labyrinthine layer blood vessel development	Vash2	IMP	MGI:MGI:3846784	Mouse	PMID:25184477
Biological Process	GO:0060711	labyrinthine layer development	Vash2	IMP	MGI:MGI:3846784	Mouse	PMID:25184477
Biological Process	GO:0060674	placenta blood vessel development	Vash2	IMP	MGI:MGI:3846784	Mouse	PMID:25184477
Biological Process	GO:0045766	positive regulation of angiogenesis	VASH2	IDA		Human	PMID:19204325
Biological Process	GO:0045766	positive regulation of angiogenesis	Vash2	IMP	MGI:MGI:3846784	Mouse	PMID:19204325
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	VASH2	IDA		Human	PMID:19204325
Biological Process	GO:0006508	proteolysis	VASH2	IDA		Human	PMID:29146869
Biological Process	GO:0006508	proteolysis	Vash2	IDA		Mouse	MGI:MGI:6102981|PMID:29146868
Biological Process	GO:0000768	syncytium formation by plasma membrane fusion	Vash2	IMP	MGI:MGI:3846784	Mouse	PMID:25184477

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern