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Vash2 Gene Detail
Summary
  • Symbol
    Vash2
  • Name
    vasohibin 2
  • Synonyms
    B130052G07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444826
    NCBI Gene: 226841
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:190947646-190979296 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 96.28 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    156 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444826
protein coding gene Chr1:190947646-190979368 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016934
protein coding gene Chr1:197958076-197994499 (-)
A/J MGP_AJ_G0016913
protein coding gene Chr1:189850482-189886445 (-)
AKR/J MGP_AKRJ_G0016878
protein coding gene Chr1:195461564-195497675 (-)
BALB/cJ MGP_BALBcJ_G0016871
protein coding gene Chr1:190526413-190558897 (-)
C3H/HeJ MGP_C3HHeJ_G0016695
protein coding gene Chr1:196318593-196351302 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017334
protein coding gene Chr1:204267415-204304441 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015041
protein coding gene Chr1:180759082-180785033 (-)
CAST/EiJ MGP_CASTEiJ_G0016278
protein coding gene Chr1:195908045-195940045 (-)
CBA/J MGP_CBAJ_G0016669
protein coding gene Chr1:211831083-211862593 (-)
DBA/2J MGP_DBA2J_G0016775
protein coding gene Chr1:188573866-188605209 (-)
FVB/NJ MGP_FVBNJ_G0016771
protein coding gene Chr1:186699205-186730692 (-)
LP/J MGP_LPJ_G0016850
protein coding gene Chr1:199133744-199168253 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016803
protein coding gene Chr1:218547083-218578750 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017371
protein coding gene Chr1:195354318-195388661 (-)
PWK/PhJ MGP_PWKPhJ_G0016065
protein coding gene Chr1:187850240-187883748 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015841
protein coding gene Chr1:194340307-194371283 (-)
WSB/EiJ MGP_WSBEiJ_G0016340
protein coding gene Chr1:195572135-195605380 (-)



Homology
more
  • Human Ortholog
    VASH2, vasohibin 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    VASH2, vasohibin 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 79805
    neXtProt AC: NX_Q86V25
    UniProt: Q86V25

  • Chr Location
    1q32.3; chr1:212935543-212991585 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice have defects in initiating angiogenesis in response to skin wounding.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037568 Ensembl Gene Model | MGI Sequence Detail 31651 C57BL/6J ±  kb
transcript ENSMUST00000166139 Ensembl | MGI Sequence Detail 3897 Not Applicable  
polypeptide ENSMUSP00000127626 Ensembl | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 60
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:282618 Zhou C, et al., Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer. Nat Commun. 2019 Jul 19;10(1):3212

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory