Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP53
  • Mouse genes Usp53
  • Rat genes Usp53
  • Zfish genes usp53b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp53

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	USP53	IPI	UniProtKB:P46108	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	USP53	IPI	UniProtKB:P46108	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	USP53	IPI	UniProtKB:P46108	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP53	IPI	UniProtKB:P46109	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP53	IPI	UniProtKB:Q5PRF9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP53	IPI	UniProtKB:P46108	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Usp53	IPI	PR:P39447	Mouse	PMID:26609154
Molecular Function	GO:0005515	protein binding	Usp53	IPI	PR:Q9Z0U1	Mouse	PMID:26609154
Cellular Component	GO:0005923	bicellular tight junction	USP53	IMP		Human	PMID:32124521
Cellular Component	GO:0005911	cell-cell junction	Usp53	IDA		Mouse	PMID:26609154
Biological Process	GO:0001508	action potential	Usp53	IMP	MGI:MGI:3708452	Mouse	PMID:26609154
Biological Process	GO:1904019	epithelial cell apoptotic process	Usp53	IMP	MGI:MGI:3708452	Mouse	PMID:26609154
Biological Process	GO:0051402	neuron apoptotic process	Usp53	IMP	MGI:MGI:3708452	Mouse	PMID:26609154
Biological Process	GO:1905584	outer hair cell apoptotic process	Usp53	IMP	MGI:MGI:3708452	Mouse	PMID:26609154
Biological Process	GO:0010996	response to auditory stimulus	Usp53	IMP	MGI:MGI:3708452	Mouse	PMID:26609154
Biological Process	GO:0007605	sensory perception of sound	Usp53	IMP	MGI:MGI:3708452	Mouse	PMID:17329413
Biological Process	GO:0007605	sensory perception of sound	Usp53	IMP	MGI:MGI:3708452	Mouse	PMID:26609154

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern