Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP12
  • Mouse genes Usp12
  • Rat genes Usp12
  • Zfish genes usp12a,usp12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP12	IDA		Human	PMID:19075014
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP12	IMP		Human	PMID:19075014
Molecular Function	GO:0101005	deubiquitinase activity	Usp12	IDA		Mouse	PMID:26811477
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:Q8TAF3	Human	PMID:19075014
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:Q8TBZ3	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:Q8TBZ3	Human	PMID:20147737
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:O60346	Human	PMID:24145035
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:Q8TAF3	Human	PMID:27373336
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:Q8TBZ3	Human	PMID:27373336
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:Q8TAF3	Human	PMID:27650958
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:Q8TBZ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:P27797	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:P36957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	USP12	IPI	UniProtKB:Q8TDX7	Human	PMID:32814053
Biological Process	GO:0016579	protein deubiquitination	USP12	IDA		Human	PMID:19075014
Biological Process	GO:0016579	protein deubiquitination	USP12	IDA		Human	PMID:24145035
Biological Process	GO:0016579	protein deubiquitination	Usp12	IDA		Mouse	PMID:26811477

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern