Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP10
  • Mouse genes Usp10
  • Rat genes Usp10
  • Zfish genes usp10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP10	IMP		Human	PMID:19398555
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP10	IDA		Human	PMID:20096447
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP10	IDA		Human	PMID:21962518
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP10	IMP		Human	PMID:25861989
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP10	IMP		Human	PMID:21962518
Molecular Function	GO:0002039	p53 binding	USP10	IPI	UniProtKB:P04637	Human	PMID:20096447
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:P13569	Human	PMID:19398555
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q13283	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q13283	Human	PMID:21455491
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q14457	Human	PMID:21962518
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q13283	Human	PMID:23279204
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86	Human	PMID:23279204
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q5D1E8	Human	PMID:24270572
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UL17	Human	PMID:24845384
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q13283	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q5D1E8	Human	PMID:25861989
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q92844	Human	PMID:25861989
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9Y4K3	Human	PMID:25861989
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9Y6K9	Human	PMID:25861989
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:P63244	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q13283	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q13283	Human	PMID:33495715
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86	Human	PMID:33495715
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q13283	Human	PMID:34799561
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86	Human	PMID:34799561
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q13283	Human	PMID:34901782
Molecular Function	GO:0005515	protein binding	USP10	IPI	UniProtKB:Q9UN86	Human	PMID:34901782
Molecular Function	GO:0003723	RNA binding	USP10	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	USP10	HDA		Human	PMID:22681889
Molecular Function	GO:0044325	transmembrane transporter binding	USP10	IDA		Human	PMID:19398555
Cellular Component	GO:0005737	cytoplasm	USP10	IDA		Human	PMID:20096447
Cellular Component	GO:0005829	cytosol	USP10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005769	early endosome	USP10	IDA		Human	PMID:19398555
Cellular Component	GO:0045111	intermediate filament cytoskeleton	USP10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	USP10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	USP10	IDA		Human	PMID:20096447
Cellular Component	GO:0005634	nucleus	USP10	IDA		Human	PMID:24845384
Cellular Component	GO:0032991	protein-containing complex	USP10	IDA		Human	PMID:25861989
Biological Process	GO:0071347	cellular response to interleukin-1	USP10	IMP		Human	PMID:25861989
Biological Process	GO:0006974	DNA damage response	USP10	IMP		Human	PMID:25861989
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	USP10	IMP		Human	PMID:20096447
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	USP10	IMP		Human	PMID:25861989
Biological Process	GO:0016579	protein deubiquitination	USP10	IMP		Human	PMID:19398555
Biological Process	GO:0016579	protein deubiquitination	USP10	IDA		Human	PMID:20096447
Biological Process	GO:0016579	protein deubiquitination	USP10	IMP		Human	PMID:24845384
Biological Process	GO:0016579	protein deubiquitination	USP10	IMP		Human	PMID:25861989
Biological Process	GO:0010506	regulation of autophagy	USP10	IDA		Human	PMID:21962518

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern