Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UNC45B
  • Mouse genes Unc45b
  • Rat genes Unc45b
  • Zfish genes unc45b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Unc45b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051879	Hsp90 protein binding	Unc45b	IDA		Mouse	PMID:18326487
Molecular Function	GO:0051879	Hsp90 protein binding	Unc45b	IDA		Mouse	PMID:18478096
Molecular Function	GO:0005515	protein binding	UNC45B	IPI	UniProtKB:P08238	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	unc45b	IPI	UniProtKB:Q90474	Zfish	PMID:17586488
Molecular Function	GO:0005515	protein binding	unc45b	IPI	UniProtKB:Q5RG12	Zfish	PMID:17586488
Molecular Function	GO:0005515	protein binding	unc45b	IPI	UniProtKB:O57521	Zfish	PMID:17586488
Cellular Component	GO:0005737	cytoplasm	unc45b	IDA		Zfish	PMID:18347070
Cellular Component	GO:0005829	cytosol	Unc45b	IDA		Mouse	PMID:18478096
Cellular Component	GO:0030018	Z disc	unc45b	IDA		Zfish	PMID:20440001
Cellular Component	GO:0030018	Z disc	unc45b	IDA		Zfish	PMID:18347070
Biological Process	GO:0048738	cardiac muscle tissue development	unc45b	IMP	ZFIN:ZDB-MRPHLNO-070423-1	Zfish	PMID:17189627
Biological Process	GO:0048738	cardiac muscle tissue development	unc45b	IMP	ZFIN:ZDB-MRPHLNO-070423-2	Zfish	PMID:17189627
Biological Process	GO:0061077	chaperone-mediated protein folding	Unc45b	IDA		Mouse	PMID:18478096
Biological Process	GO:0061077	chaperone-mediated protein folding	Unc45b	IDA		Mouse	PMID:18326487
Biological Process	GO:0002088	lens development in camera-type eye	unc45b	IMP		Zfish	PMID:24549050|ZFIN:ZDB-PUB-170525-7
Biological Process	GO:0002088	lens development in camera-type eye	unc45b	IMP	ZFIN:ZDB-GENO-100618-2	Zfish	PMID:24549050
Biological Process	GO:0055001	muscle cell development	unc45b	IMP	ZFIN:ZDB-GENO-140724-6	Zfish	PMID:24613615
Biological Process	GO:0030239	myofibril assembly	unc45b	IMP	ZFIN:ZDB-GENO-071127-9	Zfish	PMID:17586488
Biological Process	GO:0030239	myofibril assembly	unc45b	IMP	ZFIN:ZDB-GENO-140724-6	Zfish	PMID:24613615
Biological Process	GO:0030239	myofibril assembly	unc45b	IMP	ZFIN:ZDB-MRPHLNO-071127-2	Zfish	PMID:17586488
Biological Process	GO:0060538	skeletal muscle organ development	unc45b	IMP	ZFIN:ZDB-GENO-100720-6	Zfish	PMID:20440001
Biological Process	GO:0007519	skeletal muscle tissue development	unc45b	IMP	ZFIN:ZDB-MRPHLNO-070423-2	Zfish	PMID:17189627
Biological Process	GO:0007519	skeletal muscle tissue development	unc45b	IMP	ZFIN:ZDB-GENO-100618-2	Zfish	PMID:23144999
Biological Process	GO:0007519	skeletal muscle tissue development	unc45b	IMP	ZFIN:ZDB-MRPHLNO-070423-1	Zfish	PMID:17189627
Biological Process	GO:0007519	skeletal muscle tissue development	unc45b	IMP	ZFIN:ZDB-GENO-130107-1	Zfish	PMID:23144999
Biological Process	GO:0055002	striated muscle cell development	unc45b	IMP	ZFIN:ZDB-GENO-100618-2	Zfish	PMID:31644553

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern