Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UNC45A
  • Mouse genes Unc45a
  • Rat genes Unc45a
  • Zfish genes unc45a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Unc45a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	UNC45A	HDA		Human	PMID:25468996
Molecular Function	GO:0051879	Hsp90 protein binding	Unc45a	IDA		Mouse	PMID:18326487
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:P61244	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:P61244-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:Q8NA82	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:Q9UJV3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:P61244	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:Q8NA82	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:P50221	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:Q8NA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:Q969V4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UNC45A	IPI	UniProtKB:Q96HU8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Unc45a	IPI	PR:P10126	Mouse	PMID:21689717
Cellular Component	GO:0005829	cytosol	UNC45A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	UNC45A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	UNC45A	IDA		Human	GO_REF:0000052
Biological Process	GO:0001525	angiogenesis	unc45a	IMP	ZFIN:ZDB-MRPHLNO-081009-2	Zfish	PMID:18462713
Biological Process	GO:0001525	angiogenesis	unc45a	IMP	ZFIN:ZDB-GENO-980202-948	Zfish	PMID:18462713
Biological Process	GO:0001525	angiogenesis	unc45a	IMP	ZFIN:ZDB-MRPHLNO-081009-1	Zfish	PMID:18462713
Biological Process	GO:0008015	blood circulation	unc45a	IMP	ZFIN:ZDB-GENO-980202-948	Zfish	PMID:9007249
Biological Process	GO:0048514	blood vessel morphogenesis	unc45a	IMP	ZFIN:ZDB-GENO-980202-948	Zfish	PMID:18462713
Biological Process	GO:0048514	blood vessel morphogenesis	unc45a	IMP	ZFIN:ZDB-MRPHLNO-081009-1	Zfish	PMID:18462713
Biological Process	GO:0048514	blood vessel morphogenesis	unc45a	IMP	ZFIN:ZDB-MRPHLNO-081009-2	Zfish	PMID:18462713
Biological Process	GO:0051216	cartilage development	unc45a	IMP	ZFIN:ZDB-GENO-980202-948	Zfish	PMID:18462713
Biological Process	GO:0061077	chaperone-mediated protein folding	Unc45a	IDA		Mouse	PMID:18326487
Biological Process	GO:0032532	regulation of microvillus length	unc45a	IMP	ZFIN:ZDB-GENO-980202-948	Zfish	PMID:35575086
Biological Process	GO:0060627	regulation of vesicle-mediated transport	unc45a	IMP	ZFIN:ZDB-GENO-980202-948	Zfish	PMID:35575086

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern