Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UGT1A4,UGT1A5
  • Mouse genes Ugt1a5
  • Rat genes Ugt1a5
  • Zfish genes ugt1a7,ugt1ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ugt1a5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	UGT1A4	IPI	UniProtKB:P22309	Human	PMID:17179145
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A4	IDA		Human	PMID:18177842
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A4	IDA		Human	PMID:1898728
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A4	IDA		Human	PMID:22579593
Molecular Function	GO:0015020	glucuronosyltransferase activity	UGT1A4	IDA		Human	PMID:24641623
Molecular Function	GO:0015020	glucuronosyltransferase activity	ugt1ab	IDA		Zfish	PMID:24728488
Molecular Function	GO:0015020	glucuronosyltransferase activity	ugt1a7	IDA		Zfish	PMID:24728488
Molecular Function	GO:0042803	protein homodimerization activity	UGT1A4	IDA		Human	PMID:17179145
Cellular Component	GO:0005783	endoplasmic reticulum	UGT1A4	IDA		Human	PMID:17179145
Biological Process	GO:0052695	cellular glucuronidation	UGT1A4	IDA		Human	PMID:18177842
Biological Process	GO:0052695	cellular glucuronidation	UGT1A4	IDA		Human	PMID:22579593
Biological Process	GO:0052695	cellular glucuronidation	UGT1A4	IDA		Human	PMID:24641623
Biological Process	GO:0071361	cellular response to ethanol	Ugt1a5	IEP		Rat	PMID:11412396|RGD:2317026
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Ugt1a5	IEP		Rat	PMID:10100302|RGD:2317062
Biological Process	GO:0032870	cellular response to hormone stimulus	Ugt1a5	IEP		Rat	PMID:10100302|RGD:2317062
Biological Process	GO:0001889	liver development	Ugt1a5	IEP		Rat	PMID:18938141|RGD:2317023
Biological Process	GO:0014070	response to organic cyclic compound	Ugt1a5	IEP		Rat	PMID:11854140|RGD:2317024
Biological Process	GO:0070640	vitamin D3 metabolic process	UGT1A4	IDA		Human	PMID:18177842
Biological Process	GO:0070640	vitamin D3 metabolic process	UGT1A4	IDA		Human	PMID:24641623

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern