Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBR1
  • Mouse genes Ubr1
  • Rat genes Ubr1
  • Zfish genes ubr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ubr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070728	leucine binding	UBR1	IDA		Human	PMID:20298436
Molecular Function	GO:0005515	protein binding	UBR1	IPI	UniProtKB:P63146	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	UBR1	IPI	UniProtKB:P63146	Human	PMID:21422291
Molecular Function	GO:0005515	protein binding	UBR1	IPI	UniProtKB:P02766	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBR1	IPI	UniProtKB:P07686	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBR1	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ubr1	IPI	PR:P63147	Mouse	PMID:17462990
Molecular Function	GO:0005515	protein binding	Ubr1	IPI	PR:Q9Z255	Mouse	PMID:17462990
Molecular Function	GO:0005515	protein binding	Ubr1	IPI	PR:Q6WKZ8	Mouse	PMID:11689692
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Ubr1	IDA		Mouse	PMID:14585983
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Ubr1	IGI	MGI:MGI:1861099	Mouse	PMID:11689692
Cellular Component	GO:0000502	proteasome complex	Ubr1	IGI	SGD:S000003416	Mouse	PMID:11689692
Cellular Component	GO:0000151	ubiquitin ligase complex	Ubr1	IGI	MGI:MGI:1861099	Mouse	PMID:11689692
Biological Process	GO:0071233	cellular response to leucine	UBR1	IDA		Human	PMID:20298436
Biological Process	GO:0032007	negative regulation of TOR signaling	UBR1	IMP		Human	PMID:20298436
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Ubr1	IMP	MGI:MGI:2178612	Mouse	PMID:11689692
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Ubr1	IDA		Mouse	PMID:14585983

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern