Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBA3
  • Mouse genes Uba3
  • Rat genes Uba3
  • Zfish genes uba3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Uba3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	UBA3	IPI	UniProtKB:Q8TBC4	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	UBA3	IPI	UniProtKB:Q8TBC4	Human	PMID:32296183
Molecular Function	GO:0019781	NEDD8 activating enzyme activity	UBA3	IDA		Human	PMID:12740388
Molecular Function	GO:0019781	NEDD8 activating enzyme activity	UBA3	IDA		Human	PMID:10207026
Molecular Function	GO:0019781	NEDD8 activating enzyme activity	Uba3	IDA		Mouse	PMID:19245792
Molecular Function	GO:0019781	NEDD8 activating enzyme activity	Uba3	IDA		Rat	PMID:11818503|RGD:634396
Molecular Function	GO:0019781	NEDD8 activating enzyme activity	Uba3	IMP		Rat	PMID:11818503|RGD:634396
Molecular Function	GO:0016922	nuclear receptor binding	Uba3	IPI	RGD:2581|RGD:2582	Rat	PMID:11818503|RGD:634396
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:Q13564	Human	PMID:10722740
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:P61081	Human	PMID:15361859
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:P61081	Human	PMID:15694336
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:P54727	Human	PMID:16712842
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:Q969M7	Human	PMID:19250909
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:P61081	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:O14732	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:Q96FN4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:O14732	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:Q13564	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:Q96FN4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:Q9BVJ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:P02649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBA3	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Uba3	IPI	UniProtKB:Q7TSD4	Mouse	MGI:MGI:4839670|PMID:20937703
Molecular Function	GO:0046982	protein heterodimerization activity	UBA3	IPI	UniProtKB:Q13564	Human	PMID:12740388
Molecular Function	GO:0044877	protein-containing complex binding	Uba3	IMP		Rat	PMID:11818503|RGD:634396
Cellular Component	GO:0005634	nucleus	UBA3	IDA		Human	GO_REF:0000054
Cellular Component	GO:0032991	protein-containing complex	UBA3	IDA		Human	PMID:12740388
Biological Process	GO:0007113	endomitotic cell cycle	Uba3	IMP	MGI:MGI:2154503	Mouse	PMID:11696557
Biological Process	GO:0000278	mitotic cell cycle	Uba3	IMP	MGI:MGI:2154503	Mouse	PMID:11696557
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Uba3	IDA		Rat	PMID:11818503|RGD:634396
Biological Process	GO:0045116	protein neddylation	UBA3	IDA		Human	PMID:12740388
Biological Process	GO:0051726	regulation of cell cycle	Uba3	IMP	MGI:MGI:2154503	Mouse	PMID:11696557

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern