Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBA1
  • Mouse genes Uba1
  • Rat genes Uba1
  • Zfish genes uba1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Uba1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	UBA1	IPI	UniProtKB:Q9H2C0	Human	PMID:16227972
Molecular Function	GO:0005515	protein binding	UBA1	IPI	UniProtKB:P63279	Human	PMID:17956732
Molecular Function	GO:0005515	protein binding	UBA1	IPI	UniProtKB:Q76353	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	UBA1	IPI	UniProtKB:Q96FW1	Human	PMID:26752685
Molecular Function	GO:0005515	protein binding	UBA1	IPI	UniProtKB:O00308	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBA1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBA1	IPI	UniProtKB:Q96FW1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	UBA1	IPI	UniProtKB:Q9BUZ4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Uba1	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0003723	RNA binding	UBA1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	UBA1	HDA		Human	PMID:22681889
Molecular Function	GO:0004839	ubiquitin activating enzyme activity	UBA1	IDA		Human	PMID:12629039
Molecular Function	GO:0004839	ubiquitin activating enzyme activity	UBA1	IDA		Human	PMID:21685362
Molecular Function	GO:0004839	ubiquitin activating enzyme activity	UBA1	IMP		Human	PMID:33108101
Molecular Function	GO:0004839	ubiquitin activating enzyme activity	Uba1	IDA		Mouse	PMID:1511901
Cellular Component	GO:0005737	cytoplasm	UBA1	IDA		Human	PMID:1376922
Cellular Component	GO:0005737	cytoplasm	UBA1	IMP		Human	PMID:33108101
Cellular Component	GO:0005829	cytosol	UBA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030057	desmosome	UBA1	IDA		Human	PMID:1376922
Cellular Component	GO:0010008	endosome membrane	UBA1	IDA		Human	PMID:1376922
Cellular Component	GO:0070062	extracellular exosome	UBA1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	UBA1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	UBA1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	UBA1	HDA		Human	PMID:23533145
Cellular Component	GO:0000792	heterochromatin	UBA1	IDA		Human	PMID:1376922
Cellular Component	GO:0005765	lysosomal membrane	UBA1	IDA		Human	PMID:1376922
Cellular Component	GO:0005739	mitochondrion	UBA1	IDA		Human	PMID:1376922
Cellular Component	GO:0005654	nucleoplasm	UBA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	UBA1	IDA		Human	PMID:1376922
Cellular Component	GO:0005634	nucleus	UBA1	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	UBA1	IDA		Human	PMID:22456334
Cellular Component	GO:0005634	nucleus	UBA1	IMP		Human	PMID:33108101
Cellular Component	GO:0030867	rough endoplasmic reticulum membrane	UBA1	IDA		Human	PMID:1376922
Biological Process	GO:0007409	axonogenesis	uba1	IMP	ZFIN:ZDB-MRPHLNO-140605-4	Zfish	PMID:24590288
Biological Process	GO:0006974	DNA damage response	UBA1	IDA		Human	PMID:22456334
Biological Process	GO:0050727	regulation of inflammatory response	uba1	IMP	ZFIN:ZDB-GENO-211130-3	Zfish	PMID:33108101
Biological Process	GO:0050727	regulation of inflammatory response	uba1	IMP	ZFIN:ZDB-GENO-211130-2	Zfish	PMID:33108101

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern