Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUBA4A
  • Mouse genes Tuba4a
  • Rat genes Tuba4a
  • Zfish genes tuba8l2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tuba4a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Tuba4a	IPI	UniProtKB:P91153	Mouse	MGI:MGI:5688826|PMID:23874210
Molecular Function	GO:0005515	protein binding	TUBA4A	IPI	UniProtKB:P30622	Human	PMID:16455083
Molecular Function	GO:0005515	protein binding	TUBA4A	IPI	UniProtKB:Q4G4D4	Human	PMID:20855515
Molecular Function	GO:0005515	protein binding	TUBA4A	IPI	UniProtKB:Q8N4U5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TUBA4A	IPI	UniProtKB:Q8NA72	Human	PMID:30845169
Molecular Function	GO:0005515	protein binding	TUBA4A	IPI	UniProtKB:Q8N4U5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TUBA4A	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tuba4a	IPI	PR:Q9ESD7	Mouse	PMID:20405035
Molecular Function	GO:0019901	protein kinase binding	TUBA4A	IPI	UniProtKB:Q13627-2	Human	PMID:24327345
Cellular Component	GO:0005856	cytoskeleton	TUBA4A	IDA		Human	PMID:24327345
Cellular Component	GO:0070062	extracellular exosome	TUBA4A	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	TUBA4A	HDA		Human	PMID:20458337
Cellular Component	GO:0005874	microtubule	TUBA4A	IDA		Human	PMID:21525035
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBA4A	IDA		Human	GO_REF:0000052

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern