Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TTYH1
  • Mouse genes Ttyh1
  • Rat genes Ttyh1
  • Zfish genes ttyh1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ttyh1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Ttyh1	IDA		Mouse	PMID:20634317
Molecular Function	GO:0005515	protein binding	TTYH1	IPI	UniProtKB:O15354	Human	PMID:28298427
Molecular Function	GO:0072320	volume-sensitive chloride channel activity	TTYH1	IDA		Human	PMID:16219661
Cellular Component	GO:0031527	filopodium membrane	Ttyh1	IDA		Mouse	PMID:17116230
Cellular Component	GO:0032433	filopodium tip	Ttyh1	IDA		Mouse	PMID:17116230
Cellular Component	GO:0030868	smooth endoplasmic reticulum membrane	Ttyh1	IDA		Mouse	PMID:20568244
Cellular Component	GO:0045202	synapse	Ttyh1	IDA		Mouse	PMID:16635246
Cellular Component	GO:0045202	synapse	Ttyh1	EXP		Mouse	PMID:16635246
Biological Process	GO:0098609	cell-cell adhesion	Ttyh1	IDA		Mouse	PMID:17116230
Biological Process	GO:0031589	cell-substrate adhesion	Ttyh1	IDA		Mouse	PMID:17116230
Biological Process	GO:0006821	chloride transport	TTYH1	IDA		Human	PMID:16219661
Biological Process	GO:0046847	filopodium assembly	Ttyh1	IDA		Mouse	PMID:17116230
Biological Process	GO:0000278	mitotic cell cycle	Ttyh1	IMP	MGI:MGI:4818475	Mouse	PMID:20568244

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern