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Ttyh1
Gene Detail
Symbol

Name
ID
Ttyh1
tweety homolog 1 (Drosophila)
MGI:1889007
Synonyms
4930459B04Rik, 6330408P11Rik, tty
Feature Type
protein coding gene
Genetic Map
Chromosome 7
2.38 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:4119408-4136706 bp, + strand
From VEGA annotation of GRCm38

  17299 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10779  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Ttyh1

Human
homologs
Human Homolog TTYH1, tweety family member 1
NCBI Gene ID 57348
neXtProt AC  NX_Q9H313
Human Chr (Location)  19q13.4; chr19:54415426-54436719 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display embryonic lethality before implantation with arrest before the blastocyst stage and mitotic failure.
 
Interactions
Ttyh1 interacts with 280 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process cell adhesion, cell-substrate adhesion, ...
Component axon, chloride channel complex, ...
Function calcium ion binding, chloride channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (323)    Tissues (119)    Images (60)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 323
cDNA source data(77)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(80) cDNA(79) Primer pair(1)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000021913 (Evidence)
Ensembl Gene ModelENSMUSG00000030428 (Evidence)
Entrez Gene57776 (Evidence)
UniGene29729
DFCITC1574942, TC1601572, TC1594879, TC1592250, TC1741871, TC1728666
DoTSDT.103584407, DT.103584294, DT.102556129, DT.101736686, DT.101196643, DT.50316645, DT.91321979, DT.94260126, DT.91348555
NIA Mouse Gene IndexU007610
Consensus CDS ProjectCCDS20730.1, CCDS51970.1
International Mouse Knockout Project StatusTtyh1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021913 VEGA Gene Model | MGI Sequence Detail 17299 C57BL/6J ±  kb
transcript OTTMUST00000052035 VEGA | MGI Sequence Detail 2882 Not Applicable 
polypeptide OTTMUSP00000024584 VEGA | MGI Sequence Detail 460 Not Applicable 

For the selected sequences
All sequences(97) RefSeq(9) UniProt(5)
Polymorphisms
SNPs within 2kb(142 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006990 Tweety
Protein Ontology PR:000016803 protein tweety homolog 1
References
(Earliest) J:64127 Campbell HD, et al., Human and mouse homologues of the drosophila melanogaster tweety (tty) gene: A novel gene family encoding predicted transmembrane proteins. Genomics. 2000 Aug 15;68(1):89-92
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(41)
Other
accession IDs
MGI:1914663, MGI:1921927

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory