Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TTLL1
  • Mouse genes Ttll1
  • Rat genes Ttll1
  • Zfish genes ttll1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ttll1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Ttll1	IPI	PR:Q99MS8	Mouse	PMID:17360631
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	TTLL1	IDA		Human	PMID:34782749
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	Ttll1	EXP		Mouse	MGI:MGI:5897758|PMID:15890843
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	Ttll1	IDA		Mouse	PMID:30420556
Cellular Component	GO:0036064	ciliary basal body	Ttll1	IDA		Mouse	PMID:17499049
Cellular Component	GO:0005576	extracellular region	Ttll1	IMP	MGI:MGI:4461777	Mouse	MGI:MGI:6162909|PMID:29440671
Cellular Component	GO:0005874	microtubule	TTLL1	IDA		Human	PMID:34782749
Biological Process	GO:0035082	axoneme assembly	Ttll1	IMP	MGI:MGI:4461777	Mouse	PMID:20498047
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Ttll1	IGI	MGI:MGI:1918244	Mouse	PMID:30420556
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	Ttll1	IMP	MGI:MGI:4297933	Mouse	PMID:20442420
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	Ttll1	IMP	MGI:MGI:4461777	Mouse	PMID:20498047
Biological Process	GO:0030317	flagellated sperm motility	Ttll1	IMP	MGI:MGI:4297933	Mouse	PMID:20442420
Biological Process	GO:0002395	immune response in nasopharyngeal-associated lymphoid tissue	Ttll1	IMP	MGI:MGI:4461777	Mouse	PMID:29440671
Biological Process	GO:0000226	microtubule cytoskeleton organization	TTLL1	IDA		Human	PMID:34782749
Biological Process	GO:0120197	mucociliary clearance	Ttll1	IMP	MGI:MGI:4461777	Mouse	PMID:29440671
Biological Process	GO:0018095	protein polyglutamylation	Ttll1	IDA		Mouse	PMID:29593216
Biological Process	GO:0018095	protein polyglutamylation	Ttll1	IMP		Mouse	PMID:29593216
Biological Process	GO:0018095	protein polyglutamylation	Ttll1	IDA		Mouse	PMID:30420556
Biological Process	GO:0018095	protein polyglutamylation	Ttll1	IMP	MGI:MGI:4461777	Mouse	PMID:20498047
Biological Process	GO:0120222	regulation of blastocyst development	Ttll1	IMP		Mouse	PMID:29593216
Biological Process	GO:0007288	sperm axoneme assembly	Ttll1	IMP	MGI:MGI:4461777	Mouse	PMID:20498047
Biological Process	GO:0007288	sperm axoneme assembly	Ttll1	IMP	MGI:MGI:4297933	Mouse	PMID:20442420

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern