Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TTC4
  • Mouse genes Ttc4
  • Rat genes Ttc4
  • Zfish genes ttc4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ttc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TTC4	IPI	UniProtKB:P08238	Human	PMID:18320024
Molecular Function	GO:0005515	protein binding	TTC4	IPI	UniProtKB:P11142	Human	PMID:18320024
Molecular Function	GO:0005515	protein binding	TTC4	IPI	UniProtKB:Q99741	Human	PMID:18320024
Molecular Function	GO:0005515	protein binding	TTC4	IPI	UniProtKB:P08238	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	TTC4	IPI	UniProtKB:Q9UHD2	Human	PMID:29251827
Molecular Function	GO:0005515	protein binding	TTC4	IPI	UniProtKB:Q92966	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ttc4	IPI	UniProtKB:Q6PDM1	Mouse	MGI:MGI:3706282|PMID:17335777
Cellular Component	GO:0005737	cytoplasm	TTC4	IDA		Human	PMID:29251827
Cellular Component	GO:0005737	cytoplasm	Ttc4	IDA		Mouse	MGI:MGI:6356137|PMID:19390865
Cellular Component	GO:0005634	nucleus	TTC4	IDA		Human	PMID:18320024
Cellular Component	GO:0005634	nucleus	TTC4	IDA		Human	PMID:29251827
Cellular Component	GO:0005634	nucleus	Ttc4	IDA		Mouse	MGI:MGI:3706282|PMID:17335777
Cellular Component	GO:0005634	nucleus	Ttc4	IDA		Mouse	MGI:MGI:6356137|PMID:19390865
Biological Process	GO:0060271	cilium assembly	ttc4	IMP	ZFIN:ZDB-MRPHLNO-150622-11	Zfish	PMID:25860617
Biological Process	GO:0051607	defense response to virus	TTC4	IMP		Human	PMID:29251827
Biological Process	GO:0061371	determination of heart left/right asymmetry	ttc4	IMP	ZFIN:ZDB-MRPHLNO-150622-11	Zfish	PMID:25860617
Biological Process	GO:0045087	innate immune response	TTC4	IMP		Human	PMID:29251827
Biological Process	GO:0032474	otolith morphogenesis	ttc4	IMP	ZFIN:ZDB-MRPHLNO-150622-11	Zfish	PMID:25860617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern