Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TTC3
  • Mouse genes Ttc3
  • Rat genes Ttc3
  • Zfish genes ttc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ttc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TTC3	IPI	UniProtKB:P31749	Human	PMID:20059950
Molecular Function	GO:0005515	protein binding	TTC3	IPI	UniProtKB:P31751	Human	PMID:20059950
Molecular Function	GO:0005515	protein binding	TTC3	IPI	UniProtKB:Q9Y243	Human	PMID:20059950
Molecular Function	GO:0005515	protein binding	TTC3	IPI	UniProtKB:Q9HAU4	Human	PMID:30696809
Molecular Function	GO:0005515	protein binding	Ttc3	IPI	PR:P49025	Mouse	PMID:17488780
Molecular Function	GO:0005515	protein binding	Ttc3	IPI	UniProtKB:O14578	Mouse	PMID:17488780
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TTC3	IDA		Human	PMID:20059950
Cellular Component	GO:0005829	cytosol	TTC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	TTC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TTC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TTC3	IDA		Human	PMID:20059950
Cellular Component	GO:0005773	vacuole	Ttc3	IDA		Mouse	PMID:17488780
Biological Process	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	Ttc3	IDA		Mouse	PMID:17488780
Biological Process	GO:0045665	negative regulation of neuron differentiation	Ttc3	IDA		Mouse	PMID:17488780
Biological Process	GO:0070936	protein K48-linked ubiquitination	TTC3	IDA		Human	PMID:20059950
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	TTC3	IDA		Human	PMID:20059950

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern