Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSPAN8
  • Mouse genes Tspan8
  • Rat genes Tspan8
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tspan8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	Tspan8	IPI	RGD:1593249	Rat	PMID:20124479|RGD:9698434
Molecular Function	GO:0005515	protein binding	TSPAN8	IPI	UniProtKB:Q16820	Human	PMID:27180358
Molecular Function	GO:0005515	protein binding	TSPAN8	IPI	UniProtKB:O14925	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN8	IPI	UniProtKB:P32856-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN8	IPI	UniProtKB:P54315	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN8	IPI	UniProtKB:Q9NVC3	Human	PMID:32296183
Cellular Component	GO:0009986	cell surface	Tspan8	IDA		Mouse	PMID:27733379
Cellular Component	GO:0070062	extracellular exosome	TSPAN8	HDA		Human	PMID:23533145
Biological Process	GO:0030195	negative regulation of blood coagulation	Tspan8	IDA		Rat	PMID:9531564|RGD:634231
Biological Process	GO:0010468	regulation of gene expression	Tspan8	IDA		Mouse	PMID:27733379
Biological Process	GO:0007283	spermatogenesis	Tspan8	IDA		Mouse	PMID:27733379

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern