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Tspan8 Gene Detail
Summary
  • Symbol
    Tspan8
  • Name
    tetraspanin 8
  • Synonyms
    E330007O21Rik, Tm4sf3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384918
    NCBI Gene: 216350
  • Gene Overview
    MyGene.info: TSPAN8
Location & Maps
more
  • Sequence Map
    Chr10:115817284-115849893 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32610 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 63.51 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TSPAN8, tetraspanin 8
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TSPAN8, tetraspanin 8
    Orthology source: HomoloGene
  • Synonyms
    CO-029, TM4SF3
  • Links
    NCBI Gene ID: 7103
    neXtProt AC: NX_P19075

  • Chr Location
    12q21.1; chr12:71125093-71157999 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Tspan8
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034127 Ensembl Gene Model | MGI Sequence Detail 32610 C57BL/6J ±  kb
transcript ENSMUST00000179196 Ensembl | MGI Sequence Detail 1380 Not Applicable  
polypeptide ENSMUSP00000136645 Ensembl | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    376 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 57

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143915, MGI:2445135
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:133317 Garcia-Espana A, et al., Appearance of new tetraspanin genes during vertebrate evolution. Genomics. 2008 Apr;91(4):326-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory