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Tspan8 Gene Detail
Summary
  • Symbol
    Tspan8
  • Name
    tetraspanin 8
  • Synonyms
    E330007O21Rik, Tm4sf3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384918
    NCBI Gene: 216350
  • Gene Overview
    MyGene.info: TSPAN8
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:115816832-115849893 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 63.51 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    376 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384918
protein coding gene Chr10:115816817-115849893 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017741
protein coding gene Chr10:118552611-118587464 (+)
A/J MGP_AJ_G0017717
protein coding gene Chr10:114001936-114035729 (+)
AKR/J MGP_AKRJ_G0017679
protein coding gene Chr10:117289815-117322309 (+)
BALB/cJ MGP_BALBcJ_G0017680
protein coding gene Chr10:114397070-114433411 (+)
C3H/HeJ MGP_C3HHeJ_G0017505
protein coding gene Chr10:117525419-117562468 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018137
protein coding gene Chr10:122676084-122713177 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015817
protein coding gene Chr10:108617984-108649969 (+)
CAST/EiJ MGP_CASTEiJ_G0017067
protein coding gene Chr10:117780330-117816061 (+)
CBA/J MGP_CBAJ_G0017474
protein coding gene Chr10:127463282-127503876 (+)
DBA/2J MGP_DBA2J_G0017579
protein coding gene Chr10:113144097-113179959 (+)
FVB/NJ MGP_FVBNJ_G0017574
protein coding gene Chr10:112091388-112125935 (+)
LP/J MGP_LPJ_G0017654
protein coding gene Chr10:119128274-119163418 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017603
protein coding gene Chr10:130399172-130433905 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018175
protein coding gene Chr10:117352365-117388633 (+)
PWK/PhJ MGP_PWKPhJ_G0016849
protein coding gene Chr10:113224060-113262726 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016639
protein coding gene Chr10:116142417-116176731 (+)
WSB/EiJ MGP_WSBEiJ_G0017127
protein coding gene Chr10:117529749-117566028 (+)



Homology
more
  • Human Ortholog
    TSPAN8, tetraspanin 8
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TSPAN8, tetraspanin 8
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CO-029, TM4SF3
  • Links
    NCBI Gene ID: 7103
    neXtProt AC: NX_P19075
    UniProt: P19075

  • Chr Location
    12q21.1; chr12:71125093-71157999 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034127 Ensembl Gene Model | MGI Sequence Detail 33062 C57BL/6J ±  kb
transcript ENSMUST00000179196 Ensembl | MGI Sequence Detail 1381 Not Applicable  
polypeptide ENSMUSP00000136645 Ensembl | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 58

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143915, MGI:2445135
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:238221 Mutoji K, et al., TSPAN8 Expression Distinguishes Spermatogonial Stem Cells in the Prepubertal Mouse Testis. Biol Reprod. 2016 Dec;95(6):117

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory