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Tspan8
Gene Detail
 Symbol
Name
ID
Tspan8
tetraspanin 8
MGI:2384918
Synonyms E330007O21Rik, Tm4sf3
Feature Type protein coding gene
Genetic Map
Chromosome 10
63.51 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:115817284-115849893 bp, + strand
From NCBI annotation of GRCm38

  32610 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20968  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: tetraspanin
Gene Tree: Tspan8

Human
homologs
Human Homolog TSPAN8, tetraspanin 8
NCBI Gene ID 7103
neXtProt AC  NX_P19075
Human Synonyms  CO-029, TM4SF3
Human Chr (Location)  12q14.1-q21.1; chr12:71125094-71157999 (-)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Incidental mutations (data from APF )
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process negative regulation of blood coagulation
Component integral component of membrane, membrane
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
cDNA source data(57)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(57) cDNA(57)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000034127 (Evidence)
Entrez Gene216350 (Evidence)
UniGene22270
DFCITC1580347, TC1607632
DoTSDT.101375933, DT.101400158, DT.101704757, DT.101714846, DT.533466, DT.94373923
NIA Mouse Gene IndexU012029
Consensus CDS ProjectCCDS24181.1
International Mouse Knockout Project StatusTspan8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 216350 NCBI Gene Model | MGI Sequence Detail 32610 C57BL/6J ±  kb
transcript NM_146010 RefSeq | MGI Sequence Detail 1522 C57BL/6 
polypeptide Q8R3G9 UniProt | EBI | MGI Sequence Detail 235 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(385 from dbSNP Build 137)    SNPs within 2kb including multiple locations(387)
Protein-related
information
ResourceIDDescription
InterPro IPR000301 Tetraspanin
InterPro IPR018503 Tetraspanin, conserved site
InterPro IPR008952 Tetraspanin, EC2 domain
InterPro IPR018499 Tetraspanin/Peripherin
Protein Ontology PR:000016754 tetraspanin-8
Graphical View of Protein Domain Structure
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:133317 Garcia-Espana A, et al., Appearance of new tetraspanin genes during vertebrate evolution. Genomics. 2008 Apr;91(4):326-34
All references(35)
Other
accession IDs
MGI:2143915, MGI:2445135

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory