Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIO
  • Mouse genes Trio
  • Rat genes Trio
  • Zfish genes trioa,triob
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trio

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Trio	IPI	RGD:3252	Rat	PMID:15331630|RGD:1598417
Molecular Function	GO:0005515	protein binding	TRIO	IPI	UniProtKB:Q9NRI5	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	TRIO	IPI	UniProtKB:Q5VZK9	Human	PMID:19846667
Molecular Function	GO:0005515	protein binding	TRIO	IPI	UniProtKB:Q9UPS8	Human	PMID:22666460
Molecular Function	GO:0005515	protein binding	TRIO	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	Trio	IPI	UniProtKB:Q62765	Rat	PMID:31801062|RGD:150521626
Cellular Component	GO:0098978	glutamatergic synapse	TRIO	IDA		Human	PMID:26858404
Cellular Component	GO:0098978	glutamatergic synapse	TRIO	IMP		Human	PMID:26858404
Cellular Component	GO:0098978	glutamatergic synapse	Trio	IDA		Rat	PMID:27907191|RGD:155230813
Cellular Component	GO:0098978	glutamatergic synapse	Trio	IMP		Rat	PMID:27907191|RGD:155230813
Cellular Component	GO:0098794	postsynapse	Trio	IDA		Rat	PMID:27907191|RGD:155230813
Cellular Component	GO:0098794	postsynapse	Trio	IMP		Rat	PMID:27907191|RGD:155230813
Cellular Component	GO:0048786	presynaptic active zone	TRIO	IDA		Human	PMID:27907191
Cellular Component	GO:0048786	presynaptic active zone	TRIO	IMP		Human	PMID:27907191
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Trio	IDA		Rat	PMID:26858404|RGD:155230791
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Trio	IMP		Rat	PMID:26858404|RGD:155230791
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Trio	IDA		Rat	PMID:26858404|RGD:155230791
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Trio	IMP		Rat	PMID:26858404|RGD:155230791
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Trio	IMP		Mouse	MGI:MGI:5908330|PMID:22666460
Biological Process	GO:0048812	neuron projection morphogenesis	TRIO	IMP		Human	PMID:32109419
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	TRIO	IDA		Human	PMID:26858404
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	TRIO	IMP		Human	PMID:26858404

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern