Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM59
  • Mouse genes Trim59
  • Rat genes Trim59
  • Zfish genes trim59
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim59

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8IXM6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8N966	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q9UEU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8N966	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8IXM6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8N966	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q9UEU0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:A8MW99	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:O14493	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:P52815	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q14232	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q3SY46	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q5SQN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q7Z3H0-1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q7Z6G3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q86WH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8IVQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8IXM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8N2K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q8N966	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q96FI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q9UEU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM59	IPI	UniProtKB:Q9Y342	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Trim59	IPI	PR:Q9QZH6	Mouse	PMID:22588174
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim59	IDA		Mouse	PMID:22588174
Cellular Component	GO:0005783	endoplasmic reticulum	Trim59	IDA		Mouse	PMID:22588174
Biological Process	GO:0045087	innate immune response	Trim59	IDA		Mouse	MGI:MGI:5545996|PMID:18248090
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	TRIM59	IMP		Human	PMID:22588174
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	Trim59	IDA		Mouse	PMID:22588174
Biological Process	GO:0046597	negative regulation of viral entry into host cell	Trim59	IDA		Mouse	MGI:MGI:5545996|PMID:18248090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern