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Trim59 Gene Detail
Summary
  • Symbol
    Trim59
  • Name
    tripartite motif-containing 59
  • Synonyms
    2310035M22Rik, 2700022F13Rik, Mrf1, TSBF1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914199
    NCBI Gene: 66949
Location & Maps
more
  • Sequence Map
    Chr3:69035288-69044755 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      9468 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 32.16 cM, cytoband E2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TRIM59, tripartite motif containing 59
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TRIM59, tripartite motif containing 59
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IFT80L, MRF1, RNF104, TRIM57, TSBF1
  • Links
    NCBI Gene ID: 286827
    neXtProt AC: NX_Q8IWR1

  • Chr Location
    3q25.33; chr3:160435503-160449838 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    93
  • Chemically induced (other)
    1
  • Gene trapped
    88
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Trim59
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    66
  • Tissues
    50
  • cDNA Data
    118
  • Literature Summary
    5
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024493 VEGA Gene Model | MGI Sequence Detail 9468 C57BL/6J ±  kb
transcript OTTMUST00000060095 VEGA | MGI Sequence Detail 2939 Not Applicable  
polypeptide OTTMUSP00000029298 VEGA | MGI Sequence Detail 403 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    52 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031980 tripartite motif-containing protein 59
  • InterPro Domains
    IPR000315 B-box-type zinc finger
    IPR027370 RING-type zinc-finger, LisH dimerisation motif
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
    IPR017907 Zinc finger, RING-type, conserved site
Molecular
Reagents
less
  • All nucleic 118
    cDNA 118

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919808
References
more
  • Summaries
    All 39
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory