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Trim59 Gene Detail
Summary
  • Symbol
    Trim59
  • Name
    tripartite motif-containing 59
  • Synonyms
    2310035M22Rik, 2700022F13Rik, Mrf1, TSBF1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914199
    NCBI Gene: 66949
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:69035288-69044755 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 32.16 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914199
 protein coding gene Chr3:69035288-69046400 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027292
 protein coding gene Chr3:68260029-68271162 (-)
A/J MGP_AJ_G0027254
 protein coding gene Chr3:66221025-66233017 (-)
AKR/J MGP_AKRJ_G0027222
 protein coding gene Chr3:67638724-67651525 (-)
BALB/cJ MGP_BALBcJ_G0027265
 protein coding gene Chr3:66099164-66112932 (-)
C3H/HeJ MGP_C3HHeJ_G0027009
 protein coding gene Chr3:67880460-67892837 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027711
 protein coding gene Chr3:70809087-70819286 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025064
 protein coding gene Chr3:62487070-62499270 (-)
CAST/EiJ MGP_CASTEiJ_G0026456
 protein coding gene Chr3:67832751-67845564 (-)
CBA/J MGP_CBAJ_G0026984
 protein coding gene Chr3:72993374-73004800 (-)
DBA/2J MGP_DBA2J_G0027120
 protein coding gene Chr3:65728952-65740380 (-)
FVB/NJ MGP_FVBNJ_G0027088
 protein coding gene Chr3:64350522-64360155 (-)
LP/J MGP_LPJ_G0027228
 protein coding gene Chr3:69193505-69203011 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027107
 protein coding gene Chr3:77605911-77619824 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027769
 protein coding gene Chr3:67530551-67540908 (-)
PWK/PhJ MGP_PWKPhJ_G0026190
 protein coding gene Chr3:65454852-65466927 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026006
 protein coding gene Chr3:66633701-66645118 (-)
WSB/EiJ MGP_WSBEiJ_G0026534
 protein coding gene Chr3:67685208-67695300 (-)



Homology
more
  • Human Ortholog
    TRIM59, tripartite motif containing 59
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TRIM59, tripartite motif containing 59
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IFT80L, MRF1, RNF104, TRIM57, TSBF1
  • Links
    NCBI Gene ID: 286827
    neXtProt AC: NX_Q8IWR1
    UniProt: Q8IWR1

  • Chr Location
    3q25.33; chr3:160435503-160449838 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 32644
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TRIM59
  • Gene Tree
    Trim59
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    73
  • Tissues
    55
  • cDNA Data
    120
  • Literature Summary
    5
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034317 Ensembl Gene Model | MGI Sequence Detail 9468 C57BL/6J ±  kb
transcript ENSMUST00000107802 Ensembl | MGI Sequence Detail 2939 Not Applicable  
polypeptide ENSMUSP00000103432 Ensembl | MGI Sequence Detail 403 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 120
    cDNA 120

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919808
References
more
  • Summaries
    All 44
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/13/2019
MGI 6.13 		The Jackson Laboratory