Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM15
  • Mouse genes Trim15
  • Rat genes Trim15
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140313	molecular sequestering activity	TRIM15	IDA		Human	PMID:34871740
Molecular Function	GO:0005515	protein binding	TRIM15	IPI	UniProtKB:Q3B820	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM15	IPI	UniProtKB:Q6UXP7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM15	IPI	UniProtKB:Q9UJ41	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM15	IPI	UniProtKB:O15169	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRIM15	IPI	UniProtKB:Q00534	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM15	IPI	UniProtKB:Q96MY7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM15	IPI	UniProtKB:Q9BW85	Human	PMID:32296183
Molecular Function	GO:0003713	transcription coactivator activity	TRIM15	IDA		Human	PMID:23077300
Cellular Component	GO:0005634	nucleus	TRIM15	IDA		Human	PMID:34871740
Biological Process	GO:0045087	innate immune response	TRIM15	IMP		Human	PMID:18248090
Biological Process	GO:1901253	negative regulation of intracellular transport of viral material	TRIM15	IMP		Human	PMID:18248090
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	TRIM15	IDA		Human	PMID:34871740
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	TRIM15	IMP		Human	PMID:23077300
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TRIM15	IDA		Human	PMID:23077300
Biological Process	GO:1900246	positive regulation of RIG-I signaling pathway	TRIM15	IMP		Human	PMID:23077300
Biological Process	GO:0032481	positive regulation of type I interferon production	TRIM15	IMP		Human	PMID:23077300
Biological Process	GO:0044790	suppression of viral release by host	TRIM15	IDA		Human	PMID:18248090
Biological Process	GO:0044790	suppression of viral release by host	TRIM15	IMP		Human	PMID:18248090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern