Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPT1,TPT1P8
  • Mouse genes Tpt1
  • Rat genes Tpt1
  • Zfish genes tpt1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tpt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	TPT1	IDA		Human	PMID:15162379
Molecular Function	GO:0005509	calcium ion binding	TPT1	IDA		Human	PMID:15958728
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Tpt1	IPI	UniProtKB:P20263	Mouse	MGI:MGI:4946164|PMID:21076177
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P05023	Human	PMID:16730713
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:Q15382	Human	PMID:17301792
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:Q15714	Human	PMID:18325344
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P04637	Human	PMID:21081126
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P05023	Human	PMID:21278788
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P04637	Human	PMID:22451927
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P12956	Human	PMID:22451927
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P13010	Human	PMID:22451927
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P04792	Human	PMID:25277244
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P29692	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P29692-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:Q15645	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P12956	Human	PMID:27607350
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P38646	Human	PMID:27607350
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P60709	Human	PMID:27607350
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:P67809	Human	PMID:27607350
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:Q06830	Human	PMID:27607350
Molecular Function	GO:0005515	protein binding	TPT1	IPI	UniProtKB:Q9BQE3	Human	PMID:27607350
Molecular Function	GO:0005515	protein binding	Tpt1	IPI	UniProtKB:P09405	Mouse	MGI:MGI:4849323|PMID:21048921
Molecular Function	GO:0003723	RNA binding	TPT1	HDA		Human	PMID:22658674
Cellular Component	GO:0005737	cytoplasm	TPT1	IDA		Human	PMID:15162379
Cellular Component	GO:0005881	cytoplasmic microtubule	TPT1	IDA		Human	PMID:15162379
Cellular Component	GO:0005829	cytosol	TPT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	TPT1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	TPT1	IDA		Human	PMID:15319436
Cellular Component	GO:0005615	extracellular space	Tpt1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005771	multivesicular body	TPT1	IDA		Human	PMID:15319436
Cellular Component	GO:0005654	nucleoplasm	Tpt1	IDA		Mouse	MGI:MGI:4946164|PMID:21076177
Cellular Component	GO:0005634	nucleus	TPT1	IDA		Human	PMID:11598139
Cellular Component	GO:0000922	spindle pole	TPT1	IDA		Human	PMID:15162379
Biological Process	GO:2000384	negative regulation of ectoderm development	Tpt1	IMP		Mouse	MGI:MGI:4946164|PMID:21076177
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	TPT1	IMP		Human	PMID:11598139
Biological Process	GO:0009615	response to virus	TPT1	IEP		Human	PMID:16548883
Biological Process	GO:0007283	spermatogenesis	Tpt1	IEP		Rat	PMID:11503212|RGD:724749
Biological Process	GO:0019827	stem cell population maintenance	Tpt1	IMP		Mouse	MGI:MGI:4946164|PMID:21076177

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern