Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPMT
  • Mouse genes Tpmt
  • Rat genes Tpmt
  • Zfish genes tpmt.1,tpmt.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tpmt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TPMT	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TPMT	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TPMT	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	TPMT	IDA		Human	PMID:18484748
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	TPMT	IDA		Human	PMID:657528
Molecular Function	GO:0008119	thiopurine S-methyltransferase activity	TPMT	IDA		Human	PMID:18484748
Molecular Function	GO:0008119	thiopurine S-methyltransferase activity	TPMT	IDA		Human	PMID:657528
Molecular Function	GO:0008119	thiopurine S-methyltransferase activity	Tpmt	IDA		Mouse	PMID:9539138
Biological Process	GO:0014070	response to organic cyclic compound	Tpmt	IEP		Rat	PMID:3994729|RGD:2315835
Biological Process	GO:0033574	response to testosterone	Tpmt	IEP		Rat	PMID:1897245|RGD:2315834
Biological Process	GO:0006805	xenobiotic metabolic process	TPMT	IDA		Human	PMID:18484748
Biological Process	GO:0006805	xenobiotic metabolic process	TPMT	IDA		Human	PMID:657528

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern