Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPD52
  • Mouse genes Tpd52
  • Rat genes Tpd52
  • Zfish genes tpd52
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tpd52

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	TPD52	IDA		Human	PMID:15576473
Molecular Function	GO:0042802	identical protein binding	Tpd52	IPI	PR:Q62393	Mouse	PMID:9484778
Molecular Function	GO:0005515	protein binding	TPD52	IPI	UniProtKB:Q969L2	Human	PMID:12963375
Molecular Function	GO:0005515	protein binding	TPD52	IPI	UniProtKB:P08133	Human	PMID:15576473
Molecular Function	GO:0005515	protein binding	TPD52	IPI	UniProtKB:O43399-1	Human	PMID:9484778
Molecular Function	GO:0005515	protein binding	TPD52	IPI	UniProtKB:O43399-2	Human	PMID:9484778
Molecular Function	GO:0005515	protein binding	TPD52	IPI	UniProtKB:Q16890	Human	PMID:9484778
Molecular Function	GO:0005515	protein binding	TPD52	IPI	UniProtKB:Q62393	Human	PMID:9484778
Molecular Function	GO:0005515	protein binding	Tpd52	IPI	UniProtKB:Q16890	Mouse	PMID:9484778
Molecular Function	GO:0042803	protein homodimerization activity	TPD52	IDA		Human	PMID:9484778
Molecular Function	GO:0042803	protein homodimerization activity	Tpd52	IDA		Mouse	MGI:MGI:1197397|PMID:9484778
Cellular Component	GO:0005737	cytoplasm	TPD52	IDA		Human	PMID:15576473
Cellular Component	GO:0005737	cytoplasm	TPD52	IDA		Human	PMID:16112108
Cellular Component	GO:0005783	endoplasmic reticulum	TPD52	IDA		Human	PMID:10942595
Cellular Component	GO:0098978	glutamatergic synapse	Tpd52	IDA		Mouse	PMID:24413018
Cellular Component	GO:0098978	glutamatergic synapse	Tpd52	EXP		Mouse	PMID:24413018
Cellular Component	GO:0098978	glutamatergic synapse	Tpd52	IEP		Mouse	PMID:24413018
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TPD52	IDA		Human	PMID:16112108
Cellular Component	GO:0045202	synapse	Tpd52	IDA		Mouse	PMID:24413018
Cellular Component	GO:0045202	synapse	Tpd52	IEP		Mouse	PMID:24413018
Cellular Component	GO:0045202	synapse	Tpd52	EXP		Mouse	PMID:24413018
Biological Process	GO:0030183	B cell differentiation	TPD52	IEP		Human	PMID:15576473
Biological Process	GO:0008284	positive regulation of cell population proliferation	Tpd52	IDA		Mouse	PMID:17314271
Biological Process	GO:1902035	positive regulation of hematopoietic stem cell proliferation	tpd52	IMP	ZFIN:ZDB-MRPHLNO-211025-1	Zfish	PMID:33166425

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern