Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOX3
  • Mouse genes Tox3
  • Rat genes Tox3
  • Zfish genes tox3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tox3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	TOX3	IDA		Human	PMID:21172805
Molecular Function	GO:0051219	phosphoprotein binding	TOX3	IPI	UniProtKB:P16220	Human	PMID:21172805
Molecular Function	GO:0005515	protein binding	TOX3	IPI	UniProtKB:Q99966	Human	PMID:21172805
Molecular Function	GO:0005515	protein binding	Tox3	IPI	UniProtKB:Q8VHS6	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Tox3	IPI	UniProtKB:P15337	Rat	PMID:19196971|RGD:8554462
Molecular Function	GO:0005515	protein binding	Tox3	IPI	UniProtKB:Q6JHU9	Rat	PMID:19196971|RGD:8554462
Molecular Function	GO:0042803	protein homodimerization activity	TOX3	IDA		Human	PMID:21172805
Molecular Function	GO:0003713	transcription coactivator activity	TOX3	IDA		Human	PMID:21172805
Cellular Component	GO:0005829	cytosol	TOX3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TOX3	IDA		Human	GO_REF:0000052
Biological Process	GO:0019722	calcium-mediated signaling	Tox3	IDA		Rat	PMID:19196971|RGD:8554462
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	TOX3	IDA		Human	PMID:21172805
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Tox3	IDA		Rat	PMID:19196971|RGD:8554462
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TOX3	IDA		Human	PMID:21172805
Biological Process	GO:0042981	regulation of apoptotic process	TOX3	IDA		Human	PMID:21172805

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern