Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TONSL
  • Mouse genes Tonsl
  • Rat genes Tonsl
  • Zfish genes tonsl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tonsl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042393	histone binding	TONSL	IDA		Human	PMID:21055983
Molecular Function	GO:0042393	histone binding	TONSL	IDA		Human	PMID:21055984
Molecular Function	GO:0140566	histone reader activity	TONSL	IDA		Human	PMID:26527279
Molecular Function	GO:0140566	histone reader activity	TONSL	IDA		Human	PMID:27338793
Molecular Function	GO:0140566	histone reader activity	TONSL	IDA		Human	PMID:29478807
Molecular Function	GO:0005515	protein binding	TONSL	IPI	UniProtKB:Q6ZRQ5	Human	PMID:21055983
Molecular Function	GO:0005515	protein binding	TONSL	IPI	UniProtKB:Q6ZRQ5	Human	PMID:21055984
Molecular Function	GO:0005515	protein binding	TONSL	IPI	UniProtKB:Q6ZRQ5	Human	PMID:21055985
Molecular Function	GO:0005515	protein binding	TONSL	IPI	UniProtKB:Q6ZRQ5	Human	PMID:21113133
Molecular Function	GO:0005515	protein binding	TONSL	IPI	UniProtKB:Q6ZRQ5	Human	PMID:27797818
Cellular Component	GO:0016604	nuclear body	TONSL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043596	nuclear replication fork	TONSL	IDA		Human	PMID:26527279
Cellular Component	GO:0043596	nuclear replication fork	TONSL	IDA		Human	PMID:29478807
Cellular Component	GO:0043596	nuclear replication fork	TONSL	IDA		Human	PMID:21055983
Cellular Component	GO:0043596	nuclear replication fork	TONSL	IDA		Human	PMID:21055984
Cellular Component	GO:0005654	nucleoplasm	TONSL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035861	site of double-strand break	TONSL	IDA		Human	PMID:26527279
Cellular Component	GO:0035861	site of double-strand break	TONSL	IDA		Human	PMID:27338793
Cellular Component	GO:0035861	site of double-strand break	TONSL	IDA		Human	PMID:29478807
Biological Process	GO:0000724	double-strand break repair via homologous recombination	TONSL	IMP		Human	PMID:21055983
Biological Process	GO:0000724	double-strand break repair via homologous recombination	TONSL	IMP		Human	PMID:21055984
Biological Process	GO:0000724	double-strand break repair via homologous recombination	TONSL	IMP		Human	PMID:21055985
Biological Process	GO:0000724	double-strand break repair via homologous recombination	TONSL	IDA		Human	PMID:27338793
Biological Process	GO:0000724	double-strand break repair via homologous recombination	TONSL	IDA		Human	PMID:27797818
Biological Process	GO:0000724	double-strand break repair via homologous recombination	TONSL	IMP		Human	PMID:30773278
Biological Process	GO:0071168	protein localization to chromatin	TONSL	IDA		Human	PMID:27338793
Biological Process	GO:0031297	replication fork processing	TONSL	IMP		Human	PMID:21055983
Biological Process	GO:0031297	replication fork processing	TONSL	IMP		Human	PMID:21055984
Biological Process	GO:0031297	replication fork processing	TONSL	IMP		Human	PMID:21055985
Biological Process	GO:0031297	replication fork processing	TONSL	IDA		Human	PMID:27338793
Biological Process	GO:0031297	replication fork processing	TONSL	IDA		Human	PMID:29478807

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern