Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNXB
  • Mouse genes Tnxb
  • Rat genes
  • Zfish genes tnxba
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnxb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	Tnxb	IDA		Mouse	PMID:15242785
Molecular Function	GO:0098633	collagen fibril binding	TNXB	IDA		Human	PMID:16278880
Molecular Function	GO:0008201	heparin binding	Tnxb	IDA		Mouse	PMID:7512972
Molecular Function	GO:0005515	protein binding	TNXB	IPI	UniProtKB:Q8N9N5	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TNXB	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNXB	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNXB	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNXB	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNXB	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNXB	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tnxb	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0070062	extracellular exosome	TNXB	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	Tnxb	IDA		Mouse	PMID:24563484
Cellular Component	GO:0031012	extracellular matrix	Tnxb	IDA		Mouse	PMID:7512972
Cellular Component	GO:0005576	extracellular region	TNXB	HDA		Human	PMID:27068509
Cellular Component	GO:0005576	extracellular region	Tnxb	IDA		Mouse	PMID:8856503
Cellular Component	GO:0005615	extracellular space	TNXB	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	Tnxb	IDA		Mouse	PMID:7512972
Biological Process	GO:0098609	cell-cell adhesion	Tnxb	IMP	MGI:MGI:3053791	Mouse	PMID:12419962
Biological Process	GO:0007160	cell-matrix adhesion	Tnxb	IMP	MGI:MGI:3053791	Mouse	PMID:12419962
Biological Process	GO:0030199	collagen fibril organization	Tnxb	IMP	MGI:MGI:3053791	Mouse	PMID:15194424
Biological Process	GO:0030199	collagen fibril organization	Tnxb	IMP	MGI:MGI:2181283	Mouse	PMID:11925569
Biological Process	GO:0032963	collagen metabolic process	TNXB	IMP		Human	PMID:15102077
Biological Process	GO:0048251	elastic fiber assembly	TNXB	IMP		Human	PMID:15102077
Biological Process	GO:0030198	extracellular matrix organization	Tnxb	IMP	MGI:MGI:3053791	Mouse	PMID:15242785
Biological Process	GO:0006631	fatty acid metabolic process	Tnxb	IMP	MGI:MGI:3053791	Mouse	PMID:15298681
Biological Process	GO:0006629	lipid metabolic process	Tnxb	IMP	MGI:MGI:3053791	Mouse	PMID:15298681
Biological Process	GO:1904028	positive regulation of collagen fibril organization	TNXB	IDA		Human	PMID:17033827
Biological Process	GO:0043506	regulation of JUN kinase activity	Tnxb	IMP	MGI:MGI:3053791	Mouse	PMID:15212943
Biological Process	GO:0006641	triglyceride metabolic process	Tnxb	IMP	MGI:MGI:3053791	Mouse	PMID:15298681

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern