Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFSF10
  • Mouse genes Tnfsf10
  • Rat genes Tnfsf10
  • Zfish genes tnfsf10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfsf10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TNFSF10	IDA		Human	PMID:26457518
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:10549288
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O00220	Human	PMID:19427028
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:19427028
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:Q13618	Human	PMID:19427028
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:20097879
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O00220	Human	PMID:20103630
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:20103630
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:21459798
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:21525171
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:21822306
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:22266862
Molecular Function	GO:0005515	protein binding	TNFSF10	IPI	UniProtKB:O14763	Human	PMID:23678861
Molecular Function	GO:0045569	TRAIL binding	Tnfsf10	IDA		Mouse	MGI:MGI:2450205|PMID:12466268
Molecular Function	GO:0032813	tumor necrosis factor receptor superfamily binding	Tnfsf10	IPI	PR:Q9ER63	Mouse	PMID:12466268
Molecular Function	GO:0032813	tumor necrosis factor receptor superfamily binding	Tnfsf10	IPI	PR:Q9ER62	Mouse	PMID:12466268
Molecular Function	GO:0008270	zinc ion binding	TNFSF10	IDA		Human	PMID:26457518
Cellular Component	GO:0070062	extracellular exosome	TNFSF10	HDA		Human	PMID:19199708
Biological Process	GO:0008584	male gonad development	Tnfsf10	IEP		Rat	PMID:12021051|RGD:634235
Biological Process	GO:0043065	positive regulation of apoptotic process	TNFSF10	IDA		Human	PMID:21525171
Biological Process	GO:0043065	positive regulation of apoptotic process	Tnfsf10	IMP		Rat	PMID:19385008|RGD:2312745
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	TNFSF10	IDA		Human	PMID:21459798
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	TNFSF10	IDA		Human	PMID:21525171
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	TNFSF10	IDA		Human	PMID:22266862
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	TNFSF10	IDA		Human	PMID:20097879
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	TNFSF10	IDA		Human	PMID:21525171
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	TNFSF10	IDA		Human	PMID:22266862
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	Tnfsf10	IDA		Mouse	PMID:15632112
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TNFSF10	IEP		Human	PMID:12761501
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	TNFSF10	IDA		Human	PMID:22266862
Biological Process	GO:0032868	response to insulin	Tnfsf10	IEP		Rat	PMID:17352408|RGD:2312741

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern