Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFRSF11B
  • Mouse genes Tnfrsf11b
  • Rat genes Tnfrsf11b
  • Zfish genes tnfrsf11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfrsf11b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TNFRSF11B	IPI	UniProtKB:O14788	Human	PMID:22664871
Molecular Function	GO:0005515	protein binding	TNFRSF11B	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TNFRSF11B	IPI	UniProtKB:P49768-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tnfrsf11b	IPI	UniProtKB:O35235-1	Mouse	MGI:MGI:5917007|PMID:23039992
Cellular Component	GO:0031012	extracellular matrix	Tnfrsf11b	IDA		Mouse	PMID:9108485
Cellular Component	GO:0005615	extracellular space	TNFRSF11B	IDA		Human	PMID:15516325
Cellular Component	GO:0005615	extracellular space	Tnfrsf11b	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Tnfrsf11b	IDA		Rat	PMID:22353912|RGD:7205515
Cellular Component	GO:0043235	receptor complex	TNFRSF11B	IPI		Human	PMID:9168977
Biological Process	GO:0030198	extracellular matrix organization	Tnfrsf11b	IDA		Mouse	PMID:18757743
Biological Process	GO:0045779	negative regulation of bone resorption	Tnfrsf11b	IMP		Rat	PMID:11839361|RGD:730196
Biological Process	GO:0045779	negative regulation of bone resorption	Tnfrsf11b	IDA		Rat	PMID:16912914|RGD:1624170
Biological Process	GO:0042489	negative regulation of odontogenesis of dentin-containing tooth	Tnfrsf11b	IDA		Mouse	PMID:14981127
Biological Process	GO:0042489	negative regulation of odontogenesis of dentin-containing tooth	Tnfrsf11b	IEP		Rat	PMID:16283633|RGD:1624174
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	Tnfrsf11b	IDA		Mouse	MGI:MGI:6810809|PMID:9168977
Biological Process	GO:0046685	response to arsenic-containing substance	Tnfrsf11b	IEP		Rat	PMID:17190191|RGD:1624169
Biological Process	GO:0043627	response to estrogen	Tnfrsf11b	IEP		Rat	PMID:16624776|RGD:1624173
Biological Process	GO:0010035	response to inorganic substance	Tnfrsf11b	IEP		Rat	PMID:17190191|RGD:1624169
Biological Process	GO:0032026	response to magnesium ion	Tnfrsf11b	IEP		Rat	PMID:16162295|RGD:1624175
Biological Process	GO:0009612	response to mechanical stimulus	tnfrsf11b	IDA		Zfish	PMID:23632157
Biological Process	GO:0007584	response to nutrient	Tnfrsf11b	IEP		Rat	PMID:16696921|RGD:1624172
Biological Process	GO:0009410	response to xenobiotic stimulus	Tnfrsf11b	IEP		Rat	PMID:16696922|RGD:1624171

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern