Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMTC4
  • Mouse genes Tmtc4
  • Rat genes Tmtc4
  • Zfish genes tmtc4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmtc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	TMTC4	IPI	UniProtKB:P16615	Human	PMID:30188326
Molecular Function	GO:0000030	mannosyltransferase activity	TMTC4	IMP		Human	PMID:28973932
Cellular Component	GO:0005783	endoplasmic reticulum	TMTC4	IDA		Human	PMID:30188326
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	Tmtc4	IMP	MGI:MGI:5008116	Mouse	PMID:30188326
Biological Process	GO:1905584	outer hair cell apoptotic process	Tmtc4	IMP	MGI:MGI:5008116	Mouse	PMID:30188326
Biological Process	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration	Tmtc4	IMP	MGI:MGI:5008116	Mouse	PMID:30188326
Biological Process	GO:0035269	protein O-linked mannosylation	TMTC4	IMP		Human	PMID:28973932
Biological Process	GO:0007605	sensory perception of sound	Tmtc4	IGI	MGI:MGI:109247	Mouse	PMID:30188326
Biological Process	GO:0007605	sensory perception of sound	Tmtc4	IMP	MGI:MGI:5008116	Mouse	PMID:30188326

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern