Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM98
  • Mouse genes Tmem98
  • Rat genes Tmem98
  • Zfish genes tmem98
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem98

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TMEM98	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM98	IPI	UniProtKB:P08034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM98	IPI	UniProtKB:P15941-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM98	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM98	IPI	UniProtKB:P54709	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM98	IPI	UniProtKB:Q8NBJ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM98	IPI	UniProtKB:Q96L08	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tmem98	IPI	UniProtKB:Q3UR85	Mouse	MGI:MGI:6258499|PMID:30249802
Cellular Component	GO:0005783	endoplasmic reticulum	TMEM98	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Tmem98	IDA		Mouse	MGI:MGI:6258499|PMID:30249802
Cellular Component	GO:0070062	extracellular exosome	TMEM98	IDA		Human	PMID:25946230
Cellular Component	GO:0005615	extracellular space	TMEM98	IDA		Human	PMID:25946230
Cellular Component	GO:0005615	extracellular space	Tmem98	IDA		Mouse	MGI:MGI:6294180|PMID:25946230
Cellular Component	GO:0005886	plasma membrane	TMEM98	IDA		Human	PMID:25946230
Biological Process	GO:0031642	negative regulation of myelination	Tmem98	IMP		Mouse	MGI:MGI:6258499|PMID:30249802
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	Tmem98	IMP		Mouse	MGI:MGI:6258499|PMID:30249802
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	Tmem98	IDA		Mouse	MGI:MGI:6258499|PMID:30249802
Biological Process	GO:0010955	negative regulation of protein processing	Tmem98	IDA		Mouse	MGI:MGI:6258499|PMID:30249802
Biological Process	GO:0045063	T-helper 1 cell differentiation	Tmem98	IDA		Mouse	MGI:MGI:6294180|PMID:25946230

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern