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Tmem98 Gene Detail
Summary
  • Symbol
    Tmem98
  • Name
    transmembrane protein 98
  • Synonyms
    6530411B15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923457
    NCBI Gene: 103743
  • Gene Overview
    MyGene.info: TMEM98
Location & Maps
more
  • Sequence Map
    Chr11:80810175-80822033 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11859 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    TMEM98, transmembrane protein 98
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMEM98, transmembrane protein 98
    Orthology source: HomoloGene
  • Synonyms
    TADA1
  • Links
    NCBI Gene ID: 26022
    neXtProt AC: NX_Q9Y2Y6

  • Chr Location
    17q11.2; chr17:32927910-32941649 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human TMEM98 associations

Human Disease Mouse Models
       Nanophthalmos 4; NNO4   OMIM: 615972
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Tmem98
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000222 VEGA Gene Model | MGI Sequence Detail 11859 C57BL/6J ±  kb
transcript OTTMUST00000000659 VEGA | MGI Sequence Detail 1633 Not Applicable  
polypeptide OTTMUSP00000000292 VEGA | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    45 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000032065 transmembrane protein 98
  • InterPro Domains
    IPR029668 Transmembrane protein 98
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 4
Other
Accession IDs
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MGI:2144183
References
more
  • Summaries
    All 29
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:209956 Liakath-Ali K, et al., Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. Nat Commun. 2014;5:3540

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory