Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM258
  • Mouse genes Tmem258
  • Rat genes Tmem258b
  • Zfish genes tmem258
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem258

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0062062	oligosaccharyltransferase complex binding	Tmem258	IDA		Mouse	PMID:27974209
Molecular Function	GO:0005515	protein binding	TMEM258	IPI	UniProtKB:O94901|UniProtKB:Q8NF91|UniProtKB:Q8WXH0	Human	PMID:28716842
Molecular Function	GO:0005515	protein binding	TMEM258	IPI	UniProtKB:Q15041	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM258	IPI	UniProtKB:Q6ZSS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM258	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM258	IPI	UniProtKB:Q9Y5U9	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	TMEM258	IDA		Human	PMID:12427278
Cellular Component	GO:0005737	cytoplasm	TMEM258	IDA		Human	PMID:28716842
Cellular Component	GO:0005783	endoplasmic reticulum	TMEM258	IDA		Human	PMID:26472760
Cellular Component	GO:0016020	membrane	TMEM258	IDA		Human	PMID:28716842
Cellular Component	GO:0008250	oligosaccharyltransferase complex	TMEM258	IPI		Human	PMID:31831667
Cellular Component	GO:0034998	oligosaccharyltransferase I complex	TMEM258	IDA		Human	PMID:26472760
Biological Process	GO:1904019	epithelial cell apoptotic process	Tmem258	IMP	MGI:MGI:5892142	Mouse	PMID:27974209
Biological Process	GO:0006954	inflammatory response	Tmem258	IMP	MGI:MGI:5892142	Mouse	PMID:27974209
Biological Process	GO:0006487	protein N-linked glycosylation	TMEM258	IMP		Human	PMID:26472760
Biological Process	GO:0006487	protein N-linked glycosylation	TMEM258	IDA		Human	PMID:31831667
Biological Process	GO:0006487	protein N-linked glycosylation	Tmem258	IMP	MGI:MGI:5892142	Mouse	PMID:27974209
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Tmem258	IMP	MGI:MGI:5892142	Mouse	PMID:27974209

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern