Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM108
  • Mouse genes Tmem108
  • Rat genes Tmem108
  • Zfish genes tmem108
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem108

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TMEM108	IPI	UniProtKB:Q13643	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM108	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM108	IPI	UniProtKB:Q9Y680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tmem108	IPI	UniProtKB:Q5SQX6|UniProtKB:Q7TMB8	Mouse	MGI:MGI:5825407|PMID:27605705
Molecular Function	GO:0005515	protein binding	Tmem108	IPI	UniProtKB:Q62420	Mouse	MGI:MGI:5825424|PMID:21849472
Molecular Function	GO:0005515	protein binding	Tmem108	IPI	UniProtKB:Q91ZU6-2	Mouse	MGI:MGI:3703204|PMID:17287360
Cellular Component	GO:0030424	axon	Tmem108	IDA		Mouse	MGI:MGI:5825424|PMID:21849472
Cellular Component	GO:0030424	axon	Tmem108	IDA		Mouse	MGI:MGI:3703204|PMID:17287360
Cellular Component	GO:0005769	early endosome	Tmem108	IDA		Mouse	MGI:MGI:5825424|PMID:21849472
Cellular Component	GO:0010008	endosome membrane	Tmem108	IDA		Mouse	MGI:MGI:3703204|PMID:17287360
Cellular Component	GO:0014069	postsynaptic density	Tmem108	IDA		Mouse	MGI:MGI:5825380|PMID:28096412
Cellular Component	GO:0036477	somatodendritic compartment	Tmem108	IDA		Mouse	MGI:MGI:5825424|PMID:21849472
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	Tmem108	IMP		Mouse	MGI:MGI:5825407|PMID:27605705
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	Tmem108	IMP		Mouse	MGI:MGI:5825424|PMID:21849472
Biological Process	GO:0097484	dendrite extension	Tmem108	IMP		Mouse	MGI:MGI:5825407|PMID:27605705
Biological Process	GO:0097484	dendrite extension	Tmem108	IMP		Mouse	MGI:MGI:5825424|PMID:21849472
Biological Process	GO:0021542	dentate gyrus development	Tmem108	IMP		Mouse	MGI:MGI:5825380|PMID:28096412
Biological Process	GO:0098815	modulation of excitatory postsynaptic potential	Tmem108	IMP		Mouse	MGI:MGI:5825380|PMID:28096412
Biological Process	GO:0031175	neuron projection development	Tmem108	IMP		Mouse	MGI:MGI:5825407|PMID:27605705
Biological Process	GO:0031175	neuron projection development	Tmem108	IMP		Mouse	MGI:MGI:5825424|PMID:21849472
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	Tmem108	IMP		Mouse	MGI:MGI:5825407|PMID:27605705
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	Tmem108	IMP		Mouse	MGI:MGI:5825424|PMID:21849472
Biological Process	GO:0097106	postsynaptic density organization	Tmem108	IMP		Mouse	MGI:MGI:5825380|PMID:28096412
Biological Process	GO:0006898	receptor-mediated endocytosis	Tmem108	IMP		Mouse	MGI:MGI:5825407|PMID:27605705
Biological Process	GO:0008090	retrograde axonal transport	Tmem108	IDA		Mouse	MGI:MGI:3703204|PMID:17287360

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern