Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THOC1
  • Mouse genes Thoc1
  • Rat genes Da2-19,Thoc1
  • Zfish genes thoc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thoc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q13838	Human	PMID:15870275
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q8NI27	Human	PMID:15870275
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q13769	Human	PMID:19059247
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q13769	Human	PMID:19165146
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q13769	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q13769	Human	PMID:23299939
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q96BY2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q9UJ41	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q13769	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q13769	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q96BY2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:O00471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:O15481	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:O75478	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:O95994	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:P78358	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q6PI77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q6PJH3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q96BY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q9BZL4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOC1	IPI	UniProtKB:Q9H0C1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Thoc1	IPI	PR:B1AZI6	Mouse	PMID:24315442
Cellular Component	GO:0000781	chromosome, telomeric region	THOC1	IDA		Human	PMID:24270157
Cellular Component	GO:0005737	cytoplasm	THOC1	IDA		Human	PMID:15358532
Cellular Component	GO:0016607	nuclear speck	THOC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	THOC1	IDA		Human	PMID:15358532
Cellular Component	GO:0000347	THO complex	THOC1	IDA		Human	PMID:15998806
Cellular Component	GO:0000445	THO complex part of transcription export complex	THOC1	IDA		Human	PMID:15998806
Cellular Component	GO:0000346	transcription export complex	THOC1	IDA		Human	PMID:15833825
Cellular Component	GO:0000346	transcription export complex	THOC1	IDA		Human	PMID:15998806
Biological Process	GO:0006915	apoptotic process	THOC1	IDA		Human	PMID:10512864
Biological Process	GO:0006406	mRNA export from nucleus	THOC1	IDA		Human	PMID:17190602
Biological Process	GO:0006406	mRNA export from nucleus	THOC1	IMP		Human	PMID:22144908
Biological Process	GO:2000002	negative regulation of DNA damage checkpoint	THOC1	IMP		Human	PMID:22144908
Biological Process	GO:0048297	negative regulation of isotype switching to IgA isotypes	Thoc1	IMP		Mouse	MGI:MGI:5520039|PMID:22144908
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	THOC1	IMP		Human	PMID:22144908
Biological Process	GO:0000018	regulation of DNA recombination	THOC1	IMP		Human	PMID:22144908
Biological Process	GO:0032784	regulation of DNA-templated transcription elongation	THOC1	IDA		Human	PMID:15870275
Biological Process	GO:0031297	replication fork processing	THOC1	IMP		Human	PMID:22144908
Biological Process	GO:0046784	viral mRNA export from host cell nucleus	THOC1	IDA		Human	PMID:18974867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern