Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THG1L
  • Mouse genes Thg1l
  • Rat genes Thg1l
  • Zfish genes thg1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thg1l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	THG1L	IDA		Human	PMID:21059936
Molecular Function	GO:0005525	GTP binding	THG1L	IDA		Human	PMID:21059936
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	THG1L	IDA		Human	PMID:25008184
Molecular Function	GO:0042802	identical protein binding	THG1L	IPI	UniProtKB:Q9NWX6	Human	PMID:21059936
Molecular Function	GO:0042802	identical protein binding	THG1L	IPI	UniProtKB:Q9NWX6	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	THG1L	IPI	UniProtKB:Q9NWX6	Human	PMID:25416956
Molecular Function	GO:0000287	magnesium ion binding	THG1L	IDA		Human	PMID:21059936
Molecular Function	GO:0016779	nucleotidyltransferase activity	THG1L	EXP		Human	PMID:21059936
Molecular Function	GO:0005515	protein binding	THG1L	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	THG1L	IPI	UniProtKB:O95140	Human	PMID:25008184
Molecular Function	GO:0005515	protein binding	THG1L	IPI	UniProtKB:Q8IWA4	Human	PMID:25008184
Molecular Function	GO:0005515	protein binding	THG1L	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THG1L	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THG1L	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THG1L	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0008193	tRNA guanylyltransferase activity	THG1L	IDA		Human	PMID:21059936
Cellular Component	GO:0005739	mitochondrion	THG1L	IDA		Human	GO_REF:0000054
Cellular Component	GO:1990234	transferase complex	THG1L	IDA		Human	PMID:21059936
Biological Process	GO:0008053	mitochondrial fusion	THG1L	IDA		Human	PMID:25008184
Biological Process	GO:0051289	protein homotetramerization	THG1L	IPI	UniProtKB:Q9NWX6	Human	PMID:21059936
Biological Process	GO:0006979	response to oxidative stress	THG1L	IDA		Human	PMID:25008184
Biological Process	GO:1990046	stress-induced mitochondrial fusion	THG1L	IDA		Human	PMID:25008184
Biological Process	GO:0008033	tRNA processing	THG1L	IDA		Human	PMID:21059936

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern