Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TET3
  • Mouse genes Tet3
  • Rat genes Tet3
  • Zfish genes tet3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tet3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008327	methyl-CpG binding	TET3	IDA		Human	PMID:29276034
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	Tet3	IDA		Mouse	MGI:MGI:3844762|PMID:19372391
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	Tet3	IMP		Mouse	MGI:MGI:5432962|PMID:22722204
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	Tet3	IMP		Mouse	MGI:MGI:5289702|PMID:21892189
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	Tet3	IDA		Mouse	MGI:MGI:5287327|PMID:21778364
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	Tet3	IMP		Mouse	MGI:MGI:5465527|PMID:21407207
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	Tet3	IDA		Mouse	PMID:20639862
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	tet3	IMP	ZFIN:ZDB-GENO-180802-6	Zfish	PMID:28926578
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	tet3	IGI	ZFIN:ZDB-GENE-090312-98	Zfish	PMID:28926578
Molecular Function	GO:0005515	protein binding	TET3	IPI	UniProtKB:O15294	Human	PMID:23222540
Molecular Function	GO:0005515	protein binding	TET3	IPI	UniProtKB:O15294	Human	PMID:23353889
Molecular Function	GO:0005515	protein binding	TET3	IPI	UniProtKB:P51610	Human	PMID:23353889
Molecular Function	GO:0005515	protein binding	Tet3	IPI	UniProtKB:O15294	Mouse	MGI:MGI:5473922|PMID:23353889
Molecular Function	GO:0005515	protein binding	Tet3	IPI	UniProtKB:A2AA28	Mouse	MGI:MGI:6103984|PMID:28930672
Molecular Function	GO:0005515	protein binding	Tet3	IPI	PR:Q6NXI8	Mouse	PMID:23690950
Molecular Function	GO:0008270	zinc ion binding	TET3	IDA		Human	PMID:29276034
Cellular Component	GO:0005737	cytoplasm	Tet3	IDA		Mouse	MGI:MGI:5289702|PMID:21892189
Cellular Component	GO:0001939	female pronucleus	Tet3	IDA		Mouse	PMID:21321204
Cellular Component	GO:0001940	male pronucleus	Tet3	IDA		Mouse	MGI:MGI:5289702|PMID:21892189
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	tet3	IMP	ZFIN:ZDB-GENO-180802-6	Zfish	PMID:28926578
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	tet3	IGI	ZFIN:ZDB-GENE-090312-98	Zfish	PMID:28926578
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	tet3	IGI	ZFIN:ZDB-GENE-060526-109	Zfish	PMID:28926578
Biological Process	GO:0071222	cellular response to lipopolysaccharide	tet3	IMP		Zfish	PMID:27418527
Biological Process	GO:0080111	DNA demethylation	Tet3	IMP		Mouse	MGI:MGI:5432962|PMID:22722204
Biological Process	GO:0080111	DNA demethylation	Tet3	IMP		Mouse	MGI:MGI:5465527|PMID:21407207
Biological Process	GO:0080111	DNA demethylation	Tet3	IMP		Mouse	MGI:MGI:5289702|PMID:21892189
Biological Process	GO:0080111	DNA demethylation	Tet3	IDA		Mouse	PMID:20639862
Biological Process	GO:0044727	DNA demethylation of male pronucleus	Tet3	IMP		Mouse	MGI:MGI:5432962|PMID:22722204
Biological Process	GO:0044727	DNA demethylation of male pronucleus	Tet3	IMP		Mouse	MGI:MGI:5465527|PMID:21407207
Biological Process	GO:0044727	DNA demethylation of male pronucleus	Tet3	IMP		Mouse	MGI:MGI:5289702|PMID:21892189
Biological Process	GO:0098508	endothelial to hematopoietic transition	tet3	IGI	ZFIN:ZDB-GENE-090312-98	Zfish	PMID:26257178
Biological Process	GO:0030097	hemopoiesis	tet3	IGI	ZFIN:ZDB-GENE-090312-98	Zfish	PMID:26257178
Biological Process	GO:0007219	Notch signaling pathway	tet3	IMP	ZFIN:ZDB-GENO-180802-6	Zfish	PMID:28926578
Biological Process	GO:0007219	Notch signaling pathway	tet3	IGI	ZFIN:ZDB-GENE-090312-98	Zfish	PMID:28926578
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TET3	IMP		Human	PMID:23353889
Biological Process	GO:0006493	protein O-linked glycosylation	TET3	IMP		Human	PMID:23353889
Biological Process	GO:0010468	regulation of gene expression	tet3	IMP	ZFIN:ZDB-GENO-180802-6	Zfish	PMID:28926578
Biological Process	GO:0010468	regulation of gene expression	tet3	IGI	ZFIN:ZDB-GENE-090312-98	Zfish	PMID:28926578
Biological Process	GO:0032656	regulation of interleukin-13 production	tet3	IMP		Zfish	PMID:27418527
Biological Process	GO:0016055	Wnt signaling pathway	tet3	IMP	ZFIN:ZDB-GENO-180802-6	Zfish	PMID:28926578
Biological Process	GO:0016055	Wnt signaling pathway	tet3	IGI	ZFIN:ZDB-GENE-060526-109	Zfish	PMID:28926578

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern