Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TENM4
  • Mouse genes Tenm4
  • Rat genes Tenm4
  • Zfish genes tenm4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tenm4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Tenm4	IPI	PR:Q3UHK6	Mouse	PMID:12000766
Molecular Function	GO:0005515	protein binding	TENM4	IPI	UniProtKB:P17482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TENM4	IPI	UniProtKB:P56470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TENM4	IPI	UniProtKB:Q92608	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TENM4	IPI	UniProtKB:Q96SQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TENM4	IPI	UniProtKB:Q9BYE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TENM4	IPI	UniProtKB:Q9H7X3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TENM4	IPI	UniProtKB:Q9NRQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TENM4	IPI	UniProtKB:Q9NUL5-4	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	Tenm4	IDA		Mouse	MGI:MGI:5447626|PMID:12000766
Cellular Component	GO:0005737	cytoplasm	Tenm4	IDA		Mouse	MGI:MGI:5437806|PMID:22915103
Cellular Component	GO:0043005	neuron projection	Tenm4	IDA		Mouse	MGI:MGI:5437806|PMID:22915103
Cellular Component	GO:0005634	nucleus	Tenm4	IDA		Mouse	MGI:MGI:5437806|PMID:22915103
Cellular Component	GO:0005886	plasma membrane	TENM4	IDA		Human	PMID:26188006
Cellular Component	GO:0005886	plasma membrane	Tenm4	IDA		Mouse	PMID:9649432
Biological Process	GO:0007411	axon guidance	tenm4	IMP	ZFIN:ZDB-MRPHLNO-151230-7	Zfish	PMID:26188006
Biological Process	GO:0060912	cardiac cell fate specification	Tenm4	IMP	MGI:MGI:3655239	Mouse	PMID:17350578
Biological Process	GO:0060038	cardiac muscle cell proliferation	Tenm4	IMP	MGI:MGI:3655239	Mouse	PMID:17350578
Biological Process	GO:0032289	central nervous system myelin formation	TENM4	IMP		Human	PMID:26188006
Biological Process	GO:0032289	central nervous system myelin formation	Tenm4	IMP		Mouse	MGI:MGI:5437806|PMID:22915103
Biological Process	GO:0001702	gastrulation with mouth forming second	Tenm4	IMP	MGI:MGI:2449635	Mouse	PMID:15489520
Biological Process	GO:0048666	neuron development	TENM4	IMP		Human	PMID:26188006
Biological Process	GO:2000543	positive regulation of gastrulation	Tenm4	IMP		Mouse	MGI:MGI:3531238|PMID:15489520
Biological Process	GO:0031643	positive regulation of myelination	Tenm4	IMP		Mouse	MGI:MGI:5437806|PMID:22915103
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	Tenm4	IMP		Mouse	MGI:MGI:5437806|PMID:22915103
Biological Process	GO:0031641	regulation of myelination	TENM4	IMP		Human	PMID:26188006

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern