Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TCN2
  • Mouse genes Tcn2
  • Rat genes Tcn2
  • Zfish genes tcn2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tcn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140355	cargo receptor ligand activity	Tcn2	IDA		Mouse	PMID:237480
Molecular Function	GO:0031419	cobalamin binding	TCN2	IDA		Human	PMID:16537422
Molecular Function	GO:0031419	cobalamin binding	TCN2	IDA		Human	PMID:27411955
Molecular Function	GO:0031419	cobalamin binding	TCN2	IDA		Human	PMID:8443384
Molecular Function	GO:0031419	cobalamin binding	Tcn2	IDA		Mouse	PMID:21655200
Molecular Function	GO:0031419	cobalamin binding	Tcn2	IDA		Rat	PMID:11287214|RGD:1601485
Molecular Function	GO:0031419	cobalamin binding	tcn2	IDA		Zfish	PMID:30237171
Molecular Function	GO:0031419	cobalamin binding	tcn2	IDA		Zfish	PMID:22532867
Molecular Function	GO:0140104	molecular carrier activity	Tcn2	IDA		Mouse	PMID:21655200
Molecular Function	GO:0005515	protein binding	TCN2	IPI	UniProtKB:Q9NPF0	Human	PMID:27411955
Cellular Component	GO:0009897	external side of plasma membrane	Tcn2	IDA		Mouse	PMID:237480
Cellular Component	GO:0005615	extracellular space	TCN2	IDA		Human	PMID:8443384
Cellular Component	GO:0005615	extracellular space	Tcn2	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Tcn2	IDA		Mouse	PMID:21655200
Cellular Component	GO:0005615	extracellular space	Tcn2	IDA		Rat	PMID:1201244|RGD:1601486
Biological Process	GO:0015889	cobalamin transport	TCN2	IDA		Human	PMID:8443384
Biological Process	GO:0015889	cobalamin transport	Tcn2	IDA		Mouse	PMID:21655200
Biological Process	GO:0015889	cobalamin transport	Tcn2	IDA		Mouse	PMID:237480

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern