Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBPL1
  • Mouse genes Tbpl1
  • Rat genes Tbpl1
  • Zfish genes tbpl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbpl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:P52655	Human	PMID:24835508
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:P13805	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:P52655	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:P52655	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:Q9Y4Y9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBPL1	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tbpl1	IPI	PR:Q6P926	Mouse	PMID:18418073
Molecular Function	GO:0005515	protein binding	Tbpl1	IPI	PR:Q8R4I4	Mouse	PMID:15927180
Molecular Function	GO:0005515	protein binding	Tbpl1	IPI	PR:Q99PM3	Mouse	PMID:15927180
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	TBPL1	IDA		Human	PMID:15767669
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	TBPL1	IDA		Human	PMID:10220372
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	TBPL1	IDA		Human	PMID:15767669
Cellular Component	GO:0005737	cytoplasm	Tbpl1	IDA		Mouse	PMID:11861477
Cellular Component	GO:0005737	cytoplasm	Tbpl1	IDA		Mouse	PMID:18418073
Cellular Component	GO:0005737	cytoplasm	Tbpl1	IDA		Mouse	PMID:15927180
Cellular Component	GO:0001673	male germ cell nucleus	Tbpl1	IDA		Mouse	PMID:18418073
Cellular Component	GO:0005634	nucleus	Tbpl1	IDA		Mouse	PMID:11861477
Cellular Component	GO:0005672	transcription factor TFIIA complex	Tbpl1	IDA		Mouse	PMID:15927180
Biological Process	GO:0001675	acrosome assembly	Tbpl1	IMP	MGI:MGI:2182539	Mouse	PMID:11861477
Biological Process	GO:0006235	dTTP biosynthetic process	Tbpl1	IMP	MGI:MGI:2182539	Mouse	PMID:11861477
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	tbpl1	IMP		Zfish	PMID:11250159|ZFIN:ZDB-PUB-010404-14
Biological Process	GO:0007289	spermatid nucleus differentiation	Tbpl1	IMP	MGI:MGI:2181639	Mouse	PMID:16765935
Biological Process	GO:0007283	spermatogenesis	Tbpl1	IDA		Mouse	PMID:11861477
Biological Process	GO:0006366	transcription by RNA polymerase II	tbpl1	IMP		Zfish	PMID:11250159|ZFIN:ZDB-PUB-010404-14

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern