Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAOK1
  • Mouse genes Taok1
  • Rat genes Taok1
  • Zfish genes taok1a,taok1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Taok1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	TAOK1	IDA		Human	PMID:12639963
Molecular Function	GO:0048487	beta-tubulin binding	TAOK1	IDA		Human	PMID:12639963
Molecular Function	GO:0016301	kinase activity	TAOK1	IDA		Human	PMID:12639963
Molecular Function	GO:0031489	myosin V binding	Taok1	IPI	RGD:3143	Rat	PMID:24478457|RGD:11532776
Molecular Function	GO:0005515	protein binding	TAOK1	IPI	UniProtKB:Q20347	Human	PMID:11733138
Molecular Function	GO:0005515	protein binding	Taok1	IPI	UniProtKB:Q63572	Rat	PMID:18216281|RGD:13461749
Molecular Function	GO:0005515	protein binding	Taok1	IPI	UniProtKB:Q7Z699	Rat	PMID:18216281|RGD:13461749
Molecular Function	GO:0030295	protein kinase activator activity	Taok1	IMP		Rat	PMID:9786855|RGD:1299457
Molecular Function	GO:0004672	protein kinase activity	Taok1	IDA		Rat	PMID:18216281|RGD:13461749
Molecular Function	GO:0019901	protein kinase binding	Taok1	IPI	UniProtKB:Q63572	Rat	PMID:18216281|RGD:13461749
Molecular Function	GO:0019901	protein kinase binding	Taok1	IDA		Rat	PMID:9786855|RGD:1299457
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	Taok1	IDA		Rat	PMID:14517247|RGD:8553906
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Taok1	IDA		Rat	PMID:14517247|RGD:8553906
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Taok1	IMP		Rat	PMID:9786855|RGD:1299457
Cellular Component	GO:0070062	extracellular exosome	TAOK1	HDA		Human	PMID:19056867
Cellular Component	GO:0015630	microtubule cytoskeleton	TAOK1	IMP		Human	PMID:12639963
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TAOK1	IMP		Human	PMID:12639963
Biological Process	GO:0021954	central nervous system neuron development	TAOK1	IMP		Human	PMID:33565190
Biological Process	GO:0021954	central nervous system neuron development	Taok1	IMP		Mouse	MGI:MGI:6707836|PMID:33565190
Biological Process	GO:0006974	DNA damage response	TAOK1	IDA		Human	PMID:17396146
Biological Process	GO:0097194	execution phase of apoptosis	TAOK1	IDA		Human	PMID:16407310
Biological Process	GO:0000226	microtubule cytoskeleton organization	TAOK1	IMP		Human	PMID:12639963
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	TAOK1	IMP		Human	PMID:17396146
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	TAOK1	IMP		Human	PMID:12639963
Biological Process	GO:0070050	neuron cellular homeostasis	TAOK1	IMP		Human	PMID:17900936
Biological Process	GO:0016310	phosphorylation	TAOK1	IDA		Human	PMID:12639963
Biological Process	GO:0046330	positive regulation of JNK cascade	TAOK1	IDA		Human	PMID:16407310
Biological Process	GO:1901985	positive regulation of protein acetylation	TAOK1	IMP		Human	PMID:12639963
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	TAOK1	IMP		Human	PMID:17396146
Biological Process	GO:0046777	protein autophosphorylation	Taok1	IDA		Rat	PMID:18216281|RGD:13461749
Biological Process	GO:0006468	protein phosphorylation	Taok1	IMP		Rat	PMID:9786855|RGD:1299457
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Taok1	IMP		Rat	PMID:18216281|RGD:13461749
Biological Process	GO:0051493	regulation of cytoskeleton organization	Taok1	IDA		Rat	PMID:14517247|RGD:8553906
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	Taok1	IMP		Rat	PMID:18216281|RGD:13461749

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern