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Taok1
Gene Detail
Symbol

Name
ID
Taok1
TAO kinase 1
MGI:1914490
Synonyms
2810468K05Rik, D130018F14Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
46.64 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:77529162-77585506 bp, - strand
From VEGA annotation of GRCm38

  56345 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:27041  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TAOK1
Protein SuperFamily: serine/threonine-protein kinase TAO1
Gene Tree: Taok1

Human
homologs
TAOK1, TAO kinase 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 57551
neXtProt AC: NX_Q7L7X3

Human Synonyms: hKFC-B, hTAOK1, KFC-B, MAP3K16, MARKK, PSK2, PSK-2, TAO1

Human Chr (Location): 17q11.2; chr17:29390925-29551904 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(19) Targeted(3)
Genomic Mutations involving Taok1 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Taok1 interacts with 605 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process activation of MAPKK activity, activation of protein kinase activity, ...
Component cytoplasm, extracellular exosome, ...
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (147)    Tissues (20)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 147
cDNA source data(30)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase taok1    NEW 
Molecular
reagents
All nucleic(32) cDNA(31) Other(1)
Microarray probesets(12)
Other database
links
VEGA Gene Model OTTMUSG00000008181 (Evidence)
Ensembl Gene Model ENSMUSG00000017291 (Evidence)
Entrez Gene 216965 (Evidence)
DFCI TC1630192, TC1599674, TC1599641, TC1581061, TC1580095, TC1733946
DoTS DT.529438, DT.481656, DT.110519378, DT.532826
NIA Mouse Gene Index U055730
EC 2.7.11.1
Consensus CDS Project CCDS36235.1
International Mouse Phenotyping Consortium Status Taok1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008181 VEGA Gene Model | MGI Sequence Detail 56345 C57BL/6J ±  kb
transcript OTTMUST00000018584 VEGA | MGI Sequence Detail 11813 Not Applicable 
polypeptide OTTMUSP00000008535 VEGA | MGI Sequence Detail 1001 Not Applicable 

For the selected sequences
All sequences(80) RefSeq(14) UniProt(4)
Polymorphisms
SNPs within 2kb(149 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000016048 serine/threonine-protein kinase TAO1
References
(Earliest) J:43939 Gunther CV, et al., Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus. Genes Dev. 1990 Apr;4(4):667-79
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:2144401, MGI:2442256

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory