Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYTL4
  • Mouse genes Sytl4
  • Rat genes Sytl4
  • Zfish genes sytl4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sytl4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042043	neurexin family protein binding	Sytl4	IDA		Mouse	MGI:MGI:1932155|PMID:11243866
Molecular Function	GO:0005543	phospholipid binding	Sytl4	IDA		Mouse	PMID:10497219
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:O15156	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:P51116	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q8NHQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q9NP66	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q8NHQ1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q9NP66	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:A0A0C3SFZ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:O94972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:O95716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:P25800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:P51116	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:P51159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:P61764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q5MJ10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q86TI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q8WV44	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q96C00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q9H4L5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q9HAT0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q9NP66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYTL4	IPI	UniProtKB:Q9Y250	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	UniProtKB:Q9ERI2	Mouse	MGI:MGI:2176311|PMID:11773082
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	UniProtKB:Q9ERI2	Mouse	MGI:MGI:4412435|PMID:18940603
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	UniProtKB:P55258	Mouse	MGI:MGI:2176311|PMID:11773082
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	UniProtKB:P63011	Mouse	MGI:MGI:2176311|PMID:11773082
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	PR:Q9ERI2	Mouse	PMID:12590134
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	PR:P55258	Mouse	PMID:12590134
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	UniProtKB:P63012	Mouse	PMID:12590134
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	PR:O08599	Mouse	PMID:12590134
Molecular Function	GO:0005515	protein binding	Sytl4	IPI	RGD:620204|RGD:727731	Rat	PMID:15039459|RGD:4892230
Cellular Component	GO:0016324	apical plasma membrane	Sytl4	IDA		Rat	PMID:15039459|RGD:4892230
Cellular Component	GO:0005768	endosome	SYTL4	IDA		Human	PMID:19966785
Cellular Component	GO:0019898	extrinsic component of membrane	Sytl4	IDA		Mouse	MGI:MGI:1932155|PMID:11243866
Cellular Component	GO:0030141	secretory granule	Sytl4	IDA		Mouse	PMID:10497219
Cellular Component	GO:0030667	secretory granule membrane	Sytl4	IDA		Rat	PMID:15039459|RGD:4892230
Biological Process	GO:0006887	exocytosis	Sytl4	IDA		Mouse	PMID:12590134
Biological Process	GO:0030073	insulin secretion	Sytl4	IMP		Mouse	PMID:16890542
Biological Process	GO:0032418	lysosome localization	SYTL4	IMP		Human	PMID:2732579
Biological Process	GO:0071985	multivesicular body sorting pathway	SYTL4	IMP		Human	PMID:19966785
Biological Process	GO:0046676	negative regulation of insulin secretion	Sytl4	IMP		Mouse	PMID:16890542
Biological Process	GO:0001778	plasma membrane repair	SYTL4	IDA		Human	PMID:27325790
Biological Process	GO:0045921	positive regulation of exocytosis	SYTL4	IMP		Human	PMID:19966785
Biological Process	GO:0050714	positive regulation of protein secretion	SYTL4	IMP		Human	PMID:19966785
Biological Process	GO:1905684	regulation of plasma membrane repair	SYTL4	IMP		Human	PMID:2732579

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern