Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYT2
  • Mouse genes Syt2
  • Rat genes Syt2
  • Zfish genes syt2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syt2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Syt2	IDA		Mouse	PMID:15350218
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt2	IDA		Mouse	MGI:MGI:5795832|PMID:8626542
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt2	IDA		Mouse	MGI:MGI:69465|PMID:7961887
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt2	IDA		Mouse	PMID:15350218
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt2	IDA		Rat	PMID:7791877|RGD:61762
Molecular Function	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding	Syt2	IDA		Mouse	MGI:MGI:69465|PMID:7961887
Molecular Function	GO:0001786	phosphatidylserine binding	Syt2	IDA		Mouse	MGI:MGI:5780544|PMID:12860971
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q8TAC9	Human	PMID:19234194
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:O14493	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:O43561-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:O75379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:P02787	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:P11215	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:P30301	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:P78382	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q12982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q5VZY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q6UX40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q7L5A8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q8IWU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q8N138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q8NBD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q96G79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q96MX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q96PS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q9BWH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q9C0I4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q9H115	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:Q9P0B6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:P10844	Mouse	MGI:MGI:3700319|PMID:17185412
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:O35526	Mouse	MGI:MGI:3624891|PMID:16642042
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:E9PUL5	Mouse	MGI:MGI:5792766|PMID:27052163
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:P10844	Mouse	MGI:MGI:5919709|PMID:17167418
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:Q8TAC9	Mouse	MGI:MGI:3837083|PMID:19234194
Molecular Function	GO:0005515	protein binding	Syt2	IPI	PR:P83741	Mouse	PMID:15350218
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:Q9H4A3	Rat	PMID:15350218|RGD:8553276
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:Q9JIH7	Rat	PMID:15350218|RGD:8553276
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:P10844	Rat	PMID:16545378|RGD:8553591
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:P10844	Rat	PMID:17167421|RGD:13432297
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:P10844	Rat	PMID:22265973|RGD:8554021
Molecular Function	GO:0005515	protein binding	Syt2	IPI	UniProtKB:A5JGM8	Rat	PMID:23932591|RGD:13432343
Molecular Function	GO:0005515	protein binding	Syt2	IPI	RGD:2244	Rat	PMID:9303303|RGD:10054440
Molecular Function	GO:0019905	syntaxin binding	Syt2	IDA		Rat	PMID:7791877|RGD:61762
Cellular Component	GO:0030424	axon	Syt2	IDA		Mouse	PMID:23172916
Cellular Component	GO:0031594	neuromuscular junction	Syt2	IDA		Mouse	PMID:17192432
Cellular Component	GO:0031594	neuromuscular junction	Syt2	IMP		Mouse	PMID:17192432
Cellular Component	GO:0031594	neuromuscular junction	Syt2	IEP		Mouse	PMID:17192432
Cellular Component	GO:0005886	plasma membrane	Syt2	IDA		Mouse	PMID:15350218
Cellular Component	GO:0030672	synaptic vesicle membrane	Syt2	IDA		Rat	PMID:9867811|RGD:13702259
Cellular Component	GO:0043195	terminal bouton	Syt2	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Syt2	IEP		Mouse	PMID:17192432
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Syt2	IMP		Mouse	PMID:17192432
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Syt2	IDA		Mouse	PMID:17192432
Biological Process	GO:1903861	positive regulation of dendrite extension	SYT2	IDA		Human	PMID:23999003

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern