Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SUN2
  • Mouse genes Sun2
  • Rat genes Sun2
  • Zfish genes sun2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sun2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140444	cytoskeleton-nuclear membrane anchor activity	SUN2	IDA		Human	PMID:18396275
Molecular Function	GO:0042802	identical protein binding	SUN2	IPI	UniProtKB:Q9UH99	Human	PMID:22632968
Molecular Function	GO:0042802	identical protein binding	Sun2	IPI	UniProtKB:Q8BJS4-3	Mouse	MGI:MGI:5926036|PMID:26688217
Molecular Function	GO:0005521	lamin binding	SUN2	IDA		Human	PMID:19933576
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q6ZMZ3	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8NF91	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8WXH0	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:O08579	Human	PMID:19933576
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P02545	Human	PMID:19933576
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P50402	Human	PMID:19933576
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8WXH0-5	Human	PMID:19933576
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P52292	Human	PMID:20551905
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P53618	Human	PMID:20551905
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q9BTV4	Human	PMID:21391237
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P20339	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P02545	Human	PMID:22555292
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P53618	Human	PMID:22555292
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8WXH0	Human	PMID:22555292
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8NF91	Human	PMID:22632968
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8NF91-1	Human	PMID:22632968
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8WXH0	Human	PMID:22632968
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8WXH0-1	Human	PMID:22632968
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8IXM6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P20339	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P20339	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P50402	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:Q8WXH0	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	SUN2	IPI	UniProtKB:P20339	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Sun2	IPI	UniProtKB:Q6ZWQ0-1	Mouse	MGI:MGI:5926036|PMID:26688217
Molecular Function	GO:0005515	protein binding	Sun2	IPI	UniProtKB:Q60664	Mouse	MGI:MGI:6415450|PMID:29878215
Molecular Function	GO:0005515	protein binding	Sun2	IPI	PR:P48678	Mouse	PMID:16380439
Molecular Function	GO:0005515	protein binding	Sun2	IPI	PR:A2A8U2	Mouse	PMID:22349700
Cellular Component	GO:0000781	chromosome, telomeric region	Sun2	IDA		Mouse	PMID:17452644
Cellular Component	GO:0000794	condensed nuclear chromosome	Sun2	IDA		Mouse	PMID:17452644
Cellular Component	GO:0034993	meiotic nuclear membrane microtubule tethering complex	SUN2	IDA		Human	PMID:18396275
Cellular Component	GO:0005635	nuclear envelope	SUN2	IDA		Human	PMID:21610090
Cellular Component	GO:0005635	nuclear envelope	SUN2	IDA		Human	PMID:16380439
Cellular Component	GO:0005635	nuclear envelope	SUN2	IDA		Human	PMID:19933576
Cellular Component	GO:0005635	nuclear envelope	Sun2	IDA		Mouse	PMID:17452644
Cellular Component	GO:0005637	nuclear inner membrane	Sun2	IDA		Mouse	MGI:MGI:4441241|PMID:19933576
Cellular Component	GO:0031965	nuclear membrane	SUN2	IDA		Human	GO_REF:0000052
Biological Process	GO:0051642	centrosome localization	Sun2	IMP		Mouse	MGI:MGI:4888085|PMID:20724637
Biological Process	GO:0051642	centrosome localization	Sun2	IMP		Mouse	MGI:MGI:4412315|PMID:19874786
Biological Process	GO:0090292	nuclear matrix anchoring at nuclear membrane	SUN2	IDA		Human	PMID:19933576
Biological Process	GO:0031022	nuclear migration along microfilament	Sun2	IMP		Mouse	MGI:MGI:4888085|PMID:20724637
Biological Process	GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	Sun2	IMP		Mouse	MGI:MGI:4412315|PMID:19874786
Biological Process	GO:0030335	positive regulation of cell migration	Sun2	IMP		Mouse	MGI:MGI:4888085|PMID:20724637

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern