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Sun2 Gene Detail
Summary
  • Symbol
    Sun2
  • Name
    Sad1 and UNC84 domain containing 2
  • Synonyms
    B230369L08Rik, Unc84b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443011
    NCBI Gene: 223697
  • Gene Overview
    MyGene.info: SUN2
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:79724070-79742536 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    60 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443011
protein coding gene Chr15:79724068-79742536 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022084
protein coding gene Chr15:80017866-80035600 (-)
A/J MGP_AJ_G0022045
protein coding gene Chr15:77248575-77266421 (-)
AKR/J MGP_AKRJ_G0022020
protein coding gene Chr15:79411246-79429092 (-)
BALB/cJ MGP_BALBcJ_G0022051
protein coding gene Chr15:77261238-77279976 (-)
C3H/HeJ MGP_C3HHeJ_G0021822
protein coding gene Chr15:79397402-79416504 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022494
protein coding gene Chr15:83166682-83185768 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020024
protein coding gene Chr15:73731118-73749246 (-)
CAST/EiJ MGP_CASTEiJ_G0021343
protein coding gene Chr15:80110108-80127913 (-)
CBA/J MGP_CBAJ_G0021787
protein coding gene Chr15:85755963-85778131 (-)
DBA/2J MGP_DBA2J_G0021916
protein coding gene Chr15:76735418-76753316 (-)
FVB/NJ MGP_FVBNJ_G0021894
protein coding gene Chr15:75763237-75781951 (-)
LP/J MGP_LPJ_G0021984
protein coding gene Chr15:80206281-80227453 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021914
protein coding gene Chr15:90855714-90875015 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022508
protein coding gene Chr15:79431817-79450697 (-)
PWK/PhJ MGP_PWKPhJ_G0021085
protein coding gene Chr15:76746402-76764779 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020922
protein coding gene Chr15:79229752-79251070 (-)
WSB/EiJ MGP_WSBEiJ_G0021395
protein coding gene Chr15:79816311-79835136 (-)



Homology
more
  • Human Ortholog
    SUN2, Sad1 and UNC84 domain containing 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SUN2, Sad1 and UNC84 domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    UNC84B
  • Links
    NCBI Gene ID: 25777
    neXtProt AC: NX_Q9UH99
    UniProt: Q9UH99

  • Chr Location
    22q13.1; chr22:38734714-38756019 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9113
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SUN2
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    22 phenotypes from multigenic genotypes
    33 phenotype references
Mice homozygous for a null allele exhibit no gross abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042524 Ensembl Gene Model | MGI Sequence Detail 18467 C57BL/6J ±  kb
transcript ENSMUST00000046259 Ensembl | MGI Sequence Detail 3804 Not Applicable  
polypeptide ENSMUSP00000047864 Ensembl | MGI Sequence Detail 731 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    cDNA 65
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146038
References
more
  • Summaries
    All 70
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 13
    Phenotypes 33
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:263180 Dominguez Gonzalez B, et al., Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease. Hum Mol Genet. 2018 Jun 15;27(12):2154-2170

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory